Determinants of microvascular function in individuals with and without type 2 diabetes: a population-based approach

Microvascular dysfunction (impaired functioning of the small blood vessels in the body) is associated with conditions such as heart failure, stroke, cognitive impairment and depression. This dissertation is part of the Maastricht Study and examines the risk factors of microvascular dysfunction in people with and without diabetes. Elevated blood sugar levels, even in people with prediabetes, and ageing are associated with ocular and dermal microvascular dysfunction. Male gender and smoking are associated with dermal microvascular dysfunction. Early and extensive monitoring of elevated blood sugar levels and microvascular dysfunction may prevent many common diseases.