Determinants of microvascular function in individuals with and without type 2 diabetes: a population-based approach

Ben Madhu Sörensen

Research output: ThesisDoctoral ThesisInternal

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Abstract

Microvascular dysfunction (impaired functioning of the small blood vessels in the body) is associated with conditions such as heart failure, stroke, cognitive impairment and depression. This dissertation is part of the Maastricht Study and examines the risk factors of microvascular dysfunction in people with and without diabetes. Elevated blood sugar levels, even in people with prediabetes, and ageing are associated with ocular and dermal microvascular dysfunction. Male gender and smoking are associated with dermal microvascular dysfunction. Early and extensive monitoring of elevated blood sugar levels and microvascular dysfunction may prevent many common diseases.
Original languageEnglish
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • Stehouwer, Coen, Supervisor
  • Houben, Boy, Advisor
  • Schram, Miranda, Advisor
Award date31 Jan 2018
Place of PublicationMaastricht
Publisher
Print ISBNs9789492679246
DOIs
Publication statusPublished - 2018

Keywords

  • diabetes mellitus
  • blood vessels
  • microvascular dysfunction
  • risk factors

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