Abstract
Only when including quality and standardization at every level of DNA methylation analyses, will we be able to achieve the robustness to independently validate DNA methylation analyses and to compare multiple methylation studies in systematic reviews. This is the only way to more efficiently develop future DNA methylation based biomarkers.
Original language | English |
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Pages (from-to) | 933-935 |
Number of pages | 3 |
Journal | Epigenomics |
Volume | 9 |
Issue number | 7 |
DOIs | |
Publication status | Published - Jul 2017 |
Keywords
- biomarkers
- design
- DNA methylation
- epigenetics
- genomic location
- methodological challenges
- normalization
- quality
- standardization
- PROMOTER METHYLATION
- COLON-CANCER
- GENE
- GLIOMAS
- PCR
- CPG