Design, synthesis, imaging, and biomechanics of a softness-gradient hydrogel nucleus pulposus prosthesis in a canine lumbar spine model

Hendrik-Jan C. Kranenburg, Bjorn P. Meij, David Onis, Albert J. van der Veen, Ketie Saralidze, Luc A. Smolders, Julie G. Huizinga, Menno L. W. Knetsch, Peter R. Luijten, Fredy Visser, George Voorhout, Wouter J. A. Dhert, Herman A. W. Hazewinkel, Leo H. Koole

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)2148-2155
JournalJournal of Biomedical Materials Research Part B-applied Biomaterials
Volume100B
Issue number8
DOIs
Publication statusPublished - Nov 2012

Keywords

  • hydrogel
  • softness gradient
  • nucleus pulposus replacement
  • intervertebral disc
  • radiopacity

Cite this

Kranenburg, H-J. C., Meij, B. P., Onis, D., van der Veen, A. J., Saralidze, K., Smolders, L. A., Huizinga, J. G., Knetsch, M. L. W., Luijten, P. R., Visser, F., Voorhout, G., Dhert, W. J. A., Hazewinkel, H. A. W., & Koole, L. H. (2012). Design, synthesis, imaging, and biomechanics of a softness-gradient hydrogel nucleus pulposus prosthesis in a canine lumbar spine model. Journal of Biomedical Materials Research Part B-applied Biomaterials, 100B(8), 2148-2155. https://doi.org/10.1002/jbm.b.32780