Design of and technical challenges involved in a framework for multicentric radiotherapy treatment planning studies

Erik Roelofs, Lucas Persoon, Sima Qamhiyeh, Frank Verhaegen, Dirk De Ruysscher, Michael Scholz, Gheorghe Iancu, Martijn Engelsman, Coen R. Rasch, Lambert Zijp, Gert De Meerleer, Marc Coghe, Johannes A. Langendijk, Cornelis Schilstra, Madelon Pijls-Johannesma*, Philippe Lambin

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Web of Science)
41 Downloads (Pure)


This report introduces a framework for comparing radiotherapy treatment planning in multicentric in silico clinical trials. Quality assurance, data incompatibility, transfer and storage issues, and uniform analysis of results are discussed. The solutions that are given provide a useful guide for the set-up of future multicentric planning studies or public repositories of high quality data.
Original languageEnglish
Pages (from-to)567-571
JournalRadiotherapy and Oncology
Issue number3
Publication statusPublished - Dec 2010


  • Treatment planning studies
  • In silico
  • Radiotherapy
  • Multicentric
  • Clinical trial
  • Quality assurance
  • Public repositories
  • Data pooling

Cite this