Design and Rationale of the PROTECT Study: A Placebo-controlled Randomized Study of the Selective A1 Adenosine Receptor Antagonist Rolofylline for Patients Hospitalized With Acute Decompensated Heart Failure and Volume Overload to Assess Treatment Effect on Congestion and Renal Function

PROTECT Steering Committee, Stephane Heymans

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)25-35
JournalJournal of Cardiac Failure
Issue number1
Publication statusPublished - Jan 2010


  • Acute decompensated heart failure
  • adenosine A(1) receptor antagonists
  • renal function
  • rolofylline

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