Depression and Objectively Measured Physical Activity: A Systematic Review and Meta-Analysis

Vincenza Gianfredi; Lorenzo Blandi; Stefano Cacitti; Mirko Minelli; Carlo Signorelli; Andrea Amerio; Anna Odone

doi:10.3390/ijerph17103738

Depression and Objectively Measured Physical Activity: A Systematic Review and Meta-Analysis

Vincenza Gianfredi^*, Lorenzo Blandi, Stefano Cacitti, Mirko Minelli, Carlo Signorelli, Andrea Amerio, Anna Odone

^*Corresponding author for this work

Research output: Contribution to journal › (Systematic) Review article › peer-review

Abstract

Depression is a major contributor to the overall global burden of disease, with high prevalence and relapse rate. Several factors have been considered in order to reduce the depression burden. Among them, physical activity (PA) showed a potential protective role. However, evidence is contrasting probably because of the differences in PA measurement. The aim of this systematic review with meta-analysis is to assess the association between objectively measured PA and incident and prevalent depression. The systematic review was conducted according to methods recommended by the Cochrane Collaboration and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Relevant papers published through 31 August 2019 were identified searching through the electronic databases PubMed/MEDLINE, Excerpta Medica dataBASE (Embase), PsycINFO, Scopus, Web of Science (WoS), and the Cochrane Library. All analyses were conducted using ProMeta3. Finally, 42 studies met inclusion criteria. The overall Effect size (ES) of depression for the highest vs. the lowest level of PA was -1.16 [(95% CI = -1.41; -0.91), p-value <0.001] based on 37,408 participants. The results of the meta-analysis showed a potential protective effect of PA on prevalent and incident depression.

Original language	English
Article number	3738
Pages (from-to)	1-20
Number of pages	20
Journal	International Journal of Environmental Research and Public Health
Volume	17
Issue number	10
DOIs	https://doi.org/10.3390/ijerph17103738
Publication status	Published - 25 May 2020

Keywords

ADULTS
ASSOCIATIONS
CANCER SURVIVORS
EXERCISE
LIGHT
MENTAL-HEALTH
MODERATE
QUALITY-OF-LIFE
SEDENTARY BEHAVIOR
SYMPTOMS
accelerometer
depression
depressive symptoms
meta-analysis
objectively measure
physical activity

Access to Document

10.3390/ijerph17103738Licence: CC BY

Cite this

@article{965340b67a4648268c07540dcbe03c27,

title = "Depression and Objectively Measured Physical Activity: A Systematic Review and Meta-Analysis",

abstract = "Depression is a major contributor to the overall global burden of disease, with high prevalence and relapse rate. Several factors have been considered in order to reduce the depression burden. Among them, physical activity (PA) showed a potential protective role. However, evidence is contrasting probably because of the differences in PA measurement. The aim of this systematic review with meta-analysis is to assess the association between objectively measured PA and incident and prevalent depression. The systematic review was conducted according to methods recommended by the Cochrane Collaboration and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Relevant papers published through 31 August 2019 were identified searching through the electronic databases PubMed/MEDLINE, Excerpta Medica dataBASE (Embase), PsycINFO, Scopus, Web of Science (WoS), and the Cochrane Library. All analyses were conducted using ProMeta3. Finally, 42 studies met inclusion criteria. The overall Effect size (ES) of depression for the highest vs. the lowest level of PA was -1.16 [(95% CI = -1.41; -0.91), p-value <0.001] based on 37,408 participants. The results of the meta-analysis showed a potential protective effect of PA on prevalent and incident depression.",

keywords = "ADULTS, ASSOCIATIONS, CANCER SURVIVORS, EXERCISE, LIGHT, MENTAL-HEALTH, MODERATE, QUALITY-OF-LIFE, SEDENTARY BEHAVIOR, SYMPTOMS, accelerometer, depression, depressive symptoms, meta-analysis, objectively measure, physical activity",

author = "Vincenza Gianfredi and Lorenzo Blandi and Stefano Cacitti and Mirko Minelli and Carlo Signorelli and Andrea Amerio and Anna Odone",

note = "Funding Information: We conducted this systematic review according to the methods recommended by the Cochrane Collaboration [16] and to the Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines [17] and documented the process and results in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines [18]. The review protocol has been registered on PROSPERO [19], the International Prospective Register of Systematic Reviews funded by the National Institute of Health Research (https://www.crd.york.ac.uk/prospero/). Publisher Copyright: {\textcopyright} 2020 by the authors. Licensee MDPI, Basel, Switzerland.",

year = "2020",

month = may,

day = "25",

doi = "10.3390/ijerph17103738",

language = "English",

volume = "17",

pages = "1--20",

journal = "International Journal of Environmental Research and Public Health",

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TY - JOUR

T1 - Depression and Objectively Measured Physical Activity

T2 - A Systematic Review and Meta-Analysis

AU - Gianfredi, Vincenza

AU - Blandi, Lorenzo

AU - Cacitti, Stefano

AU - Minelli, Mirko

AU - Signorelli, Carlo

AU - Amerio, Andrea

AU - Odone, Anna

N1 - Funding Information: We conducted this systematic review according to the methods recommended by the Cochrane Collaboration [16] and to the Meta-analysis Of Observational Studies in Epidemiology (MOOSE) guidelines [17] and documented the process and results in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines [18]. The review protocol has been registered on PROSPERO [19], the International Prospective Register of Systematic Reviews funded by the National Institute of Health Research (https://www.crd.york.ac.uk/prospero/). Publisher Copyright: © 2020 by the authors. Licensee MDPI, Basel, Switzerland.

PY - 2020/5/25

Y1 - 2020/5/25

N2 - Depression is a major contributor to the overall global burden of disease, with high prevalence and relapse rate. Several factors have been considered in order to reduce the depression burden. Among them, physical activity (PA) showed a potential protective role. However, evidence is contrasting probably because of the differences in PA measurement. The aim of this systematic review with meta-analysis is to assess the association between objectively measured PA and incident and prevalent depression. The systematic review was conducted according to methods recommended by the Cochrane Collaboration and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Relevant papers published through 31 August 2019 were identified searching through the electronic databases PubMed/MEDLINE, Excerpta Medica dataBASE (Embase), PsycINFO, Scopus, Web of Science (WoS), and the Cochrane Library. All analyses were conducted using ProMeta3. Finally, 42 studies met inclusion criteria. The overall Effect size (ES) of depression for the highest vs. the lowest level of PA was -1.16 [(95% CI = -1.41; -0.91), p-value <0.001] based on 37,408 participants. The results of the meta-analysis showed a potential protective effect of PA on prevalent and incident depression.

AB - Depression is a major contributor to the overall global burden of disease, with high prevalence and relapse rate. Several factors have been considered in order to reduce the depression burden. Among them, physical activity (PA) showed a potential protective role. However, evidence is contrasting probably because of the differences in PA measurement. The aim of this systematic review with meta-analysis is to assess the association between objectively measured PA and incident and prevalent depression. The systematic review was conducted according to methods recommended by the Cochrane Collaboration and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. Relevant papers published through 31 August 2019 were identified searching through the electronic databases PubMed/MEDLINE, Excerpta Medica dataBASE (Embase), PsycINFO, Scopus, Web of Science (WoS), and the Cochrane Library. All analyses were conducted using ProMeta3. Finally, 42 studies met inclusion criteria. The overall Effect size (ES) of depression for the highest vs. the lowest level of PA was -1.16 [(95% CI = -1.41; -0.91), p-value <0.001] based on 37,408 participants. The results of the meta-analysis showed a potential protective effect of PA on prevalent and incident depression.

KW - ADULTS

KW - ASSOCIATIONS

KW - CANCER SURVIVORS

KW - EXERCISE

KW - LIGHT

KW - MENTAL-HEALTH

KW - MODERATE

KW - QUALITY-OF-LIFE

KW - SEDENTARY BEHAVIOR

KW - SYMPTOMS

KW - accelerometer

KW - depression

KW - depressive symptoms

KW - meta-analysis

KW - objectively measure

KW - physical activity

U2 - 10.3390/ijerph17103738

DO - 10.3390/ijerph17103738

M3 - (Systematic) Review article

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SN - 1660-4601

VL - 17

SP - 1

EP - 20

JO - International Journal of Environmental Research and Public Health

JF - International Journal of Environmental Research and Public Health

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M1 - 3738

ER -