Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH

Suzanne Aarts, Myrthe Reiche, Myrthe den Toom, Marion Gijbels, Linda Beckers, Norbert Gerdes, Esther Lutgens*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number14702
Number of pages11
JournalScientific Reports
Volume9
DOIs
Publication statusPublished - 11 Oct 2019

Keywords

  • REGULATORY T-CELLS
  • ADIPOSE-TISSUE INFLAMMATION
  • RECEPTOR CD40
  • OBESITY
  • ACTIVATION
  • STEATOSIS
  • HYPERCHOLESTEROLEMIA
  • COSTIMULATION
  • MACROPHAGES
  • SUPPRESSION

Cite this

Aarts, Suzanne ; Reiche, Myrthe ; den Toom, Myrthe ; Gijbels, Marion ; Beckers, Linda ; Gerdes, Norbert ; Lutgens, Esther. / Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH. In: Scientific Reports. 2019 ; Vol. 9.
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title = "Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH",
keywords = "REGULATORY T-CELLS, ADIPOSE-TISSUE INFLAMMATION, RECEPTOR CD40, OBESITY, ACTIVATION, STEATOSIS, HYPERCHOLESTEROLEMIA, COSTIMULATION, MACROPHAGES, SUPPRESSION",
author = "Suzanne Aarts and Myrthe Reiche and {den Toom}, Myrthe and Marion Gijbels and Linda Beckers and Norbert Gerdes and Esther Lutgens",
year = "2019",
month = "10",
day = "11",
doi = "10.1038/s41598-019-50976-6",
language = "English",
volume = "9",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",

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Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH. / Aarts, Suzanne; Reiche, Myrthe; den Toom, Myrthe; Gijbels, Marion; Beckers, Linda; Gerdes, Norbert; Lutgens, Esther.

In: Scientific Reports, Vol. 9, 14702, 11.10.2019.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH

AU - Aarts, Suzanne

AU - Reiche, Myrthe

AU - den Toom, Myrthe

AU - Gijbels, Marion

AU - Beckers, Linda

AU - Gerdes, Norbert

AU - Lutgens, Esther

PY - 2019/10/11

Y1 - 2019/10/11

KW - REGULATORY T-CELLS

KW - ADIPOSE-TISSUE INFLAMMATION

KW - RECEPTOR CD40

KW - OBESITY

KW - ACTIVATION

KW - STEATOSIS

KW - HYPERCHOLESTEROLEMIA

KW - COSTIMULATION

KW - MACROPHAGES

KW - SUPPRESSION

U2 - 10.1038/s41598-019-50976-6

DO - 10.1038/s41598-019-50976-6

M3 - Article

VL - 9

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 14702

ER -