Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians

Lucas S. Aparicio, Lutgarde Thijs, Jose Boggia, Lotte Jacobs, Jessica Barochiner, Augustine N. Odili, Jose Alfie, Kei Asayama, Paula E. Cuffaro, Kyoko Nomura, Takayoshi Ohkubo, Ichiro Tsuji, George S. Stergiou, Masahiro Kikuya, Yutaka Imai, Gabriel D. Waisman, Jan A. Staessen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


To generate outcome-driven thresholds for home blood pressure (BP) in the elderly, we analyzed 375 octogenarians (60.3% women; 83.0 years [mean]) enrolled in the International Database on home BP in relation to cardiovascular outcome. Over 5.5 years (median), 155 participants died, 76 from cardiovascular causes, whereas 104, 55, 36, and 51 experienced a cardiovascular, cardiac, coronary, or cerebrovascular event, respectively. In 202 untreated participants, home diastolic in the lowest fifth of the distribution (65.1 mmHg) compared with the multivariable-adjusted average risk was associated with increased risk of cardiovascular mortality and morbidity (hazard ratios [HRs], 1.96; P0.022), whereas the HR for cardiovascular mortality in the top fifth (82.0 mmHg) was 0.37 (P=0.034). Among 173 participants treated for hypertension, the HR for total mortality in the lowest fifth of systolic home BP (
Original languageEnglish
Pages (from-to)865-873
Issue number4
Publication statusPublished - Oct 2015


  • aged
  • aged 80 and over
  • cardiovascular diseases
  • home
  • blood pressure monitoring
  • hypertension

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