Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians

Lucas S. Aparicio; Lutgarde Thijs; Jose Boggia; Lotte Jacobs; Jessica Barochiner; Augustine N. Odili; Jose Alfie; Kei Asayama; Paula E. Cuffaro; Kyoko Nomura; Takayoshi Ohkubo; Ichiro Tsuji; George S. Stergiou; Masahiro Kikuya; Yutaka Imai; Gabriel D. Waisman; Jan A. Staessen

doi:10.1161/HYPERTENSIONAHA.115.05800

Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians

Lucas S. Aparicio, Lutgarde Thijs, Jose Boggia, Lotte Jacobs, Jessica Barochiner, Augustine N. Odili, Jose Alfie, Kei Asayama, Paula E. Cuffaro, Kyoko Nomura, Takayoshi Ohkubo, Ichiro Tsuji, George S. Stergiou, Masahiro Kikuya, Yutaka Imai, Gabriel D. Waisman, Jan A. Staessen^*

^*Corresponding author for this work

Epidemiologie

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

To generate outcome-driven thresholds for home blood pressure (BP) in the elderly, we analyzed 375 octogenarians (60.3% women; 83.0 years [mean]) enrolled in the International Database on home BP in relation to cardiovascular outcome. Over 5.5 years (median), 155 participants died, 76 from cardiovascular causes, whereas 104, 55, 36, and 51 experienced a cardiovascular, cardiac, coronary, or cerebrovascular event, respectively. In 202 untreated participants, home diastolic in the lowest fifth of the distribution (65.1 mmHg) compared with the multivariable-adjusted average risk was associated with increased risk of cardiovascular mortality and morbidity (hazard ratios [HRs], 1.96; P0.022), whereas the HR for cardiovascular mortality in the top fifth (82.0 mmHg) was 0.37 (P=0.034). Among 173 participants treated for hypertension, the HR for total mortality in the lowest fifth of systolic home BP (

Original language	English
Pages (from-to)	865-873
Journal	Hypertension
Volume	66
Issue number	4
DOIs	https://doi.org/10.1161/HYPERTENSIONAHA.115.05800
Publication status	Published - Oct 2015

Keywords

aged
aged 80 and over
cardiovascular diseases
home
blood pressure monitoring
hypertension

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10.1161/HYPERTENSIONAHA.115.05800

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Aparicio, L. S., Thijs, L., Boggia, J., Jacobs, L., Barochiner, J., Odili, A. N., Alfie, J., Asayama, K., Cuffaro, P. E., Nomura, K., Ohkubo, T., Tsuji, I., Stergiou, G. S., Kikuya, M., Imai, Y., Waisman, G. D., & Staessen, J. A. (2015). Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians. Hypertension, 66(4), 865-873. https://doi.org/10.1161/HYPERTENSIONAHA.115.05800

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title = "Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians",

abstract = "To generate outcome-driven thresholds for home blood pressure (BP) in the elderly, we analyzed 375 octogenarians (60.3% women; 83.0 years [mean]) enrolled in the International Database on home BP in relation to cardiovascular outcome. Over 5.5 years (median), 155 participants died, 76 from cardiovascular causes, whereas 104, 55, 36, and 51 experienced a cardiovascular, cardiac, coronary, or cerebrovascular event, respectively. In 202 untreated participants, home diastolic in the lowest fifth of the distribution (65.1 mmHg) compared with the multivariable-adjusted average risk was associated with increased risk of cardiovascular mortality and morbidity (hazard ratios [HRs], 1.96; P0.022), whereas the HR for cardiovascular mortality in the top fifth (82.0 mmHg) was 0.37 (P=0.034). Among 173 participants treated for hypertension, the HR for total mortality in the lowest fifth of systolic home BP (",

keywords = "aged, aged 80 and over, cardiovascular diseases, home, blood pressure monitoring, hypertension",

author = "Aparicio, {Lucas S.} and Lutgarde Thijs and Jose Boggia and Lotte Jacobs and Jessica Barochiner and Odili, {Augustine N.} and Jose Alfie and Kei Asayama and Cuffaro, {Paula E.} and Kyoko Nomura and Takayoshi Ohkubo and Ichiro Tsuji and Stergiou, {George S.} and Masahiro Kikuya and Yutaka Imai and Waisman, {Gabriel D.} and Staessen, {Jan A.}",

year = "2015",

month = oct,

doi = "10.1161/HYPERTENSIONAHA.115.05800",

language = "English",

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Aparicio, LS, Thijs, L, Boggia, J, Jacobs, L, Barochiner, J, Odili, AN, Alfie, J, Asayama, K, Cuffaro, PE, Nomura, K, Ohkubo, T, Tsuji, I, Stergiou, GS, Kikuya, M, Imai, Y, Waisman, GD & Staessen, JA 2015, 'Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians', Hypertension, vol. 66, no. 4, pp. 865-873. https://doi.org/10.1161/HYPERTENSIONAHA.115.05800

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T1 - Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians

AU - Aparicio, Lucas S.

AU - Thijs, Lutgarde

AU - Boggia, Jose

AU - Jacobs, Lotte

AU - Barochiner, Jessica

AU - Odili, Augustine N.

AU - Alfie, Jose

AU - Asayama, Kei

AU - Cuffaro, Paula E.

AU - Nomura, Kyoko

AU - Ohkubo, Takayoshi

AU - Tsuji, Ichiro

AU - Stergiou, George S.

AU - Kikuya, Masahiro

AU - Imai, Yutaka

AU - Waisman, Gabriel D.

AU - Staessen, Jan A.

PY - 2015/10

Y1 - 2015/10

N2 - To generate outcome-driven thresholds for home blood pressure (BP) in the elderly, we analyzed 375 octogenarians (60.3% women; 83.0 years [mean]) enrolled in the International Database on home BP in relation to cardiovascular outcome. Over 5.5 years (median), 155 participants died, 76 from cardiovascular causes, whereas 104, 55, 36, and 51 experienced a cardiovascular, cardiac, coronary, or cerebrovascular event, respectively. In 202 untreated participants, home diastolic in the lowest fifth of the distribution (65.1 mmHg) compared with the multivariable-adjusted average risk was associated with increased risk of cardiovascular mortality and morbidity (hazard ratios [HRs], 1.96; P0.022), whereas the HR for cardiovascular mortality in the top fifth (82.0 mmHg) was 0.37 (P=0.034). Among 173 participants treated for hypertension, the HR for total mortality in the lowest fifth of systolic home BP (

AB - To generate outcome-driven thresholds for home blood pressure (BP) in the elderly, we analyzed 375 octogenarians (60.3% women; 83.0 years [mean]) enrolled in the International Database on home BP in relation to cardiovascular outcome. Over 5.5 years (median), 155 participants died, 76 from cardiovascular causes, whereas 104, 55, 36, and 51 experienced a cardiovascular, cardiac, coronary, or cerebrovascular event, respectively. In 202 untreated participants, home diastolic in the lowest fifth of the distribution (65.1 mmHg) compared with the multivariable-adjusted average risk was associated with increased risk of cardiovascular mortality and morbidity (hazard ratios [HRs], 1.96; P0.022), whereas the HR for cardiovascular mortality in the top fifth (82.0 mmHg) was 0.37 (P=0.034). Among 173 participants treated for hypertension, the HR for total mortality in the lowest fifth of systolic home BP (

KW - aged

KW - aged 80 and over

KW - cardiovascular diseases

KW - home

KW - blood pressure monitoring

KW - hypertension

U2 - 10.1161/HYPERTENSIONAHA.115.05800

DO - 10.1161/HYPERTENSIONAHA.115.05800

M3 - Article

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SN - 0194-911X

VL - 66

SP - 865

EP - 873

JO - Hypertension

JF - Hypertension

IS - 4

ER -

Defining Thresholds for Home Blood Pressure Monitoring in Octogenarians

Abstract

Keywords

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