Defective Zn2+ homeostasis in mouse and human platelets with alpha- and delta-storage pool diseases

Sanjeev Kiran Gotru; Johanna P. van Geffen; Magdolna Nagy; Elmina Mammadova-Bach; Julia Eilenberger; Julia Volz; Georgi Manukjan; Harald Schulze; Leonard Wagner; Stefan Eber; Christian Schambeck; Carsten Deppermann; Sanne Brouns; Paquita Nurden; Andreas Greinacher; Ulrich Sachs; Bernhard Nieswandt; Heike M. Hermanns; Johan W. M. Heemskerk; Attila Braun

doi:10.1038/s41598-019-44751-w

Defective Zn2+ homeostasis in mouse and human platelets with alpha- and delta-storage pool diseases

Sanjeev Kiran Gotru, Johanna P. van Geffen, Magdolna Nagy, Elmina Mammadova-Bach, Julia Eilenberger, Julia Volz, Georgi Manukjan, Harald Schulze, Leonard Wagner, Stefan Eber, Christian Schambeck, Carsten Deppermann, Sanne Brouns, Paquita Nurden, Andreas Greinacher, Ulrich Sachs, Bernhard Nieswandt, Heike M. Hermanns, Johan W. M. Heemskerk, Attila Braun^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	8333
Number of pages	7
Journal	Scientific Reports
Volume	9
DOIs	https://doi.org/10.1038/s41598-019-44751-w
Publication status	Published - 6 Jun 2019

Keywords

ZINC
METALLOTHIONEIN
HEMOSTASIS
ACTIVATION
SECRETION
NBEAL2
PLASMA
ROLES

Access to Document

10.1038/s41598-019-44751-w

Cite this

Gotru, S. K., van Geffen, J. P., Nagy, M., Mammadova-Bach, E., Eilenberger, J., Volz, J., Manukjan, G., Schulze, H., Wagner, L., Eber, S., Schambeck, C., Deppermann, C., Brouns, S., Nurden, P., Greinacher, A., Sachs, U., Nieswandt, B., Hermanns, H. M., Heemskerk, J. W. M., & Braun, A. (2019). Defective Zn2+ homeostasis in mouse and human platelets with alpha- and delta-storage pool diseases. Scientific Reports, 9, [8333]. https://doi.org/10.1038/s41598-019-44751-w

Gotru, Sanjeev Kiran ; van Geffen, Johanna P. ; Nagy, Magdolna ; Mammadova-Bach, Elmina ; Eilenberger, Julia ; Volz, Julia ; Manukjan, Georgi ; Schulze, Harald ; Wagner, Leonard ; Eber, Stefan ; Schambeck, Christian ; Deppermann, Carsten ; Brouns, Sanne ; Nurden, Paquita ; Greinacher, Andreas ; Sachs, Ulrich ; Nieswandt, Bernhard ; Hermanns, Heike M. ; Heemskerk, Johan W. M. ; Braun, Attila. / Defective Zn2+ homeostasis in mouse and human platelets with alpha- and delta-storage pool diseases. In: Scientific Reports. 2019 ; Vol. 9.

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title = "Defective Zn2+ homeostasis in mouse and human platelets with alpha- and delta-storage pool diseases",

keywords = "ZINC, METALLOTHIONEIN, HEMOSTASIS, ACTIVATION, SECRETION, NBEAL2, PLASMA, ROLES",

author = "Gotru, {Sanjeev Kiran} and {van Geffen}, {Johanna P.} and Magdolna Nagy and Elmina Mammadova-Bach and Julia Eilenberger and Julia Volz and Georgi Manukjan and Harald Schulze and Leonard Wagner and Stefan Eber and Christian Schambeck and Carsten Deppermann and Sanne Brouns and Paquita Nurden and Andreas Greinacher and Ulrich Sachs and Bernhard Nieswandt and Hermanns, {Heike M.} and Heemskerk, {Johan W. M.} and Attila Braun",

year = "2019",

month = jun,

day = "6",

doi = "10.1038/s41598-019-44751-w",

language = "English",

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journal = "Scientific Reports",

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Gotru, SK, van Geffen, JP, Nagy, M, Mammadova-Bach, E, Eilenberger, J, Volz, J, Manukjan, G, Schulze, H, Wagner, L, Eber, S, Schambeck, C, Deppermann, C, Brouns, S, Nurden, P, Greinacher, A, Sachs, U, Nieswandt, B, Hermanns, HM, Heemskerk, JWM & Braun, A 2019, 'Defective Zn2+ homeostasis in mouse and human platelets with alpha- and delta-storage pool diseases', Scientific Reports, vol. 9, 8333. https://doi.org/10.1038/s41598-019-44751-w

Defective Zn2+ homeostasis in mouse and human platelets with alpha- and delta-storage pool diseases. / Gotru, Sanjeev Kiran; van Geffen, Johanna P.; Nagy, Magdolna; Mammadova-Bach, Elmina; Eilenberger, Julia; Volz, Julia; Manukjan, Georgi; Schulze, Harald; Wagner, Leonard; Eber, Stefan; Schambeck, Christian; Deppermann, Carsten; Brouns, Sanne; Nurden, Paquita; Greinacher, Andreas; Sachs, Ulrich; Nieswandt, Bernhard; Hermanns, Heike M.; Heemskerk, Johan W. M.; Braun, Attila.

In: Scientific Reports, Vol. 9, 8333, 06.06.2019.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Defective Zn2+ homeostasis in mouse and human platelets with alpha- and delta-storage pool diseases

AU - Gotru, Sanjeev Kiran

AU - van Geffen, Johanna P.

AU - Nagy, Magdolna

AU - Mammadova-Bach, Elmina

AU - Eilenberger, Julia

AU - Volz, Julia

AU - Manukjan, Georgi

AU - Schulze, Harald

AU - Wagner, Leonard

AU - Eber, Stefan

AU - Schambeck, Christian

AU - Deppermann, Carsten

AU - Brouns, Sanne

AU - Nurden, Paquita

AU - Greinacher, Andreas

AU - Sachs, Ulrich

AU - Nieswandt, Bernhard

AU - Hermanns, Heike M.

AU - Heemskerk, Johan W. M.

AU - Braun, Attila

PY - 2019/6/6

Y1 - 2019/6/6

KW - ZINC

KW - METALLOTHIONEIN

KW - HEMOSTASIS

KW - ACTIVATION

KW - SECRETION

KW - NBEAL2

KW - PLASMA

KW - ROLES

U2 - 10.1038/s41598-019-44751-w

DO - 10.1038/s41598-019-44751-w

M3 - Article

C2 - 31171812

VL - 9

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

M1 - 8333

ER -