Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: The role of KCC2 and GABA(A) receptor-mediated inhibition

S. P. Janssen; S. Gerard; M. E. Raijmakers; M. Truin; M. Van Kleef; E. A. Joosten

doi:10.1016/j.neuint.2011.11.006

Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: The role of KCC2 and GABA(A) receptor-mediated inhibition

S. P. Janssen^*, S. Gerard, M. E. Raijmakers, M. Truin, M. Van Kleef, E. A. Joosten

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	21-30
Journal	Neurochemistry International
Volume	60
Issue number	1
DOIs	https://doi.org/10.1016/j.neuint.2011.11.006
Publication status	Published - Jan 2012

Keywords

Rats
Chronic neuropathic pain
Spinal cord stimulation
GABA
GABA(A) receptor
KCC2

Access to Document

10.1016/j.neuint.2011.11.006

Cite this

Janssen, S. P., Gerard, S., Raijmakers, M. E., Truin, M., Van Kleef, M., & Joosten, E. A. (2012). Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: The role of KCC2 and GABA(A) receptor-mediated inhibition. Neurochemistry International, 60(1), 21-30. https://doi.org/10.1016/j.neuint.2011.11.006

Janssen, S. P. ; Gerard, S. ; Raijmakers, M. E. ; Truin, M. ; Van Kleef, M. ; Joosten, E. A. / Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: The role of KCC2 and GABA(A) receptor-mediated inhibition. In: Neurochemistry International. 2012 ; Vol. 60, No. 1. pp. 21-30.

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title = "Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: The role of KCC2 and GABA(A) receptor-mediated inhibition",

keywords = "Rats, Chronic neuropathic pain, Spinal cord stimulation, GABA, GABA(A) receptor, KCC2",

author = "Janssen, {S. P.} and S. Gerard and Raijmakers, {M. E.} and M. Truin and {Van Kleef}, M. and Joosten, {E. A.}",

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Janssen, SP, Gerard, S, Raijmakers, ME, Truin, M, Van Kleef, M & Joosten, EA 2012, 'Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: The role of KCC2 and GABA(A) receptor-mediated inhibition', Neurochemistry International, vol. 60, no. 1, pp. 21-30. https://doi.org/10.1016/j.neuint.2011.11.006

Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: The role of KCC2 and GABA(A) receptor-mediated inhibition. / Janssen, S. P.; Gerard, S.; Raijmakers, M. E.; Truin, M.; Van Kleef, M.; Joosten, E. A.

In: Neurochemistry International, Vol. 60, No. 1, 01.2012, p. 21-30.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Truin, M.

AU - Van Kleef, M.

AU - Joosten, E. A.

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Janssen SP, Gerard S, Raijmakers ME, Truin M, Van Kleef M , Joosten EA. Decreased intracellular GABA levels contribute to spinal cord stimulation-induced analgesia in rats suffering from painful peripheral neuropathy: The role of KCC2 and GABA(A) receptor-mediated inhibition. Neurochemistry International. 2012 Jan;60(1):21-30. https://doi.org/10.1016/j.neuint.2011.11.006