Data integration with biological pathways

M.P. van Iersel

Research output: ThesisDoctoral ThesisInternal

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Abstract

Biological experiments generate many data, but unfortunately these are not always optimally used. That is why BiGCaT, the Bio-informatics department of UM, has developed new software in collaboration with the Gladstone institute in San Francisco. This new software can link these data to dozens of online databases. Moreover, the data are attractively presented on illustrations that represent the processes in the cell, the so-called biological pathways. These illustrations are made by means of a specially developed wiki. With our software, two earlier studies into long-term food shortage were joined together. This reanalysis has led to new insights, without the need for an expensive experiment. The results will contribute to a better treatment of patients that have problems absorbing food due to illness.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • Mariman, Edwin, Supervisor
  • Evelo, Chris, Advisor
Award date5 Nov 2010
Place of PublicationMaastricht
Publisher
Publication statusPublished - 1 Jan 2010

Keywords

  • food shortage
  • biological data
  • software

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