Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era

David Azria*, Ariane Lapierre, Sophie Gourgou, Dirk De Ruysscher, Jacques Colinge, Philippe Lambin, Muriel Brengues, Tim Ward, Soren M. Bentzen, Hubert Thierens, Tiziana Rancati, Christopher J. Talbot, Ana Vega, Sarah L. Kerns, Christian Nicolaj Andreassen, Jenny Chang-Claude, Catharine M. L. West, Corey M. Gill, Barry S. Rosenstein

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Original languageEnglish
Article number83
Number of pages11
JournalFrontiers in Oncology
Volume7
DOIs
Publication statusPublished - 27 Apr 2017

Keywords

  • trial design
  • patient selection
  • biomarkers
  • radiotherapy
  • toxicity tests
  • GENOME-WIDE ASSOCIATION
  • NORMAL TISSUE-REACTIONS
  • BREAST-CANCER PATIENTS
  • TARGETED INTRAOPERATIVE RADIOTHERAPY
  • SINGLE NUCLEOTIDE POLYMORPHISMS
  • RANDOMIZED CONTROLLED-TRIAL
  • PROSTATE-CANCER
  • IN-VITRO
  • PHASE-II
  • CHROMOSOMAL RADIOSENSITIVITY

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