Data-analysis strategies for image-based cell profiling

Juan C. Caicedo, Sam Cooper, Florian Heigwer, Scott Warchal, Peng Qiu, Csaba Molnar, Aliaksei S. Vasilevich, Joseph D. Barry, Harmanjit Singh Bansal, Oren Kraus, Mathias Wawer, Lassi Paavolainen, Markus D. Herrmann, Mohammad Rohban, Jane Hung, Holger Hennig, John Concannon, Ian Smith, Paul A. Clemons, Shantanu SinghPaul Rees, Peter Horvath, Roger G. Linington, Anne E. Carpenter*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

Original languageEnglish
Pages (from-to)849-863
Number of pages15
JournalNature Methods
Volume14
Issue number9
DOIs
Publication statusPublished - Sep 2017

Keywords

  • HIGH-THROUGHPUT MICROSCOPY
  • HIGH-CONTENT SCREENS
  • DRUG RESPONSES
  • ILLUMINATION-CORRECTION
  • NORMALIZATION METHODS
  • GENETIC INTERACTIONS
  • STATISTICAL-METHODS
  • FUNCTIONAL-ANALYSIS
  • SOFTWARE TOOLS
  • ASSAY QUALITY

Cite this

Caicedo, J. C., Cooper, S., Heigwer, F., Warchal, S., Qiu, P., Molnar, C., Vasilevich, A. S., Barry, J. D., Bansal, H. S., Kraus, O., Wawer, M., Paavolainen, L., Herrmann, M. D., Rohban, M., Hung, J., Hennig, H., Concannon, J., Smith, I., Clemons, P. A., ... Carpenter, A. E. (2017). Data-analysis strategies for image-based cell profiling. Nature Methods, 14(9), 849-863. https://doi.org/10.1038/NMETH.4397