Abstract
To obtain a real-time noninvasive analysis of the content of the aqueous humor (AH) in the eye, a confocal dark-field ophthalmic probe was designed and optimized by ray-tracing software. The confocal technique allows Raman spectrometric sampling of the AH with suppressing signals from the surrounding tissues. Dark-field illumination prevents the excitation light to reach the vulnerable retinal tissue directly. In order to evaluate the optical performance and safety of this method, a functional prototyped eye contact probe has been designed and tested on ex vivo rabbit eyes. (C) 2020 Society of Photo-Optical Instrumentation Engineers (SPIE)
Original language | English |
---|---|
Article number | 092002 |
Number of pages | 9 |
Journal | Optical Engineering |
Volume | 59 |
Issue number | 9 |
DOIs | |
Publication status | Published - Sept 2020 |
Keywords
- Raman spectroscopy
- eye
- aqueous humor
- confocal microscopy
- dark-field illumination
- TISSUES
- GLUCOSE