Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells

Saurabh Vig; Mijke Buitinga; Dieter Rondas; Inne Crevecoeur; Marc van Zandvoort; Etienne Waelkens; Decio L. Eizirik; Conny Gysemans; Pieter Baatsen; Chantal Mathieu; Lut Overbergh

doi:10.1038/s41419-019-1518-0

Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells

Saurabh Vig, Mijke Buitinga, Dieter Rondas, Inne Crevecoeur, Marc van Zandvoort, Etienne Waelkens, Decio L. Eizirik, Conny Gysemans, Pieter Baatsen, Chantal Mathieu, Lut Overbergh^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	309
Pages (from-to)	1-13
Number of pages	13
Journal	Cell Death & Disease
Volume	10
DOIs	https://doi.org/10.1038/s41419-019-1518-0
Publication status	Published - 5 Apr 2019

Keywords

ENDOPLASMIC-RETICULUM STRESS
COOH-TERMINAL DOMAIN
SURFACE GRP78
MONOCLONAL-ANTIBODY
PROTEIN BIP
CANCER
LIGATION
PROLIFERATION
ESTABLISHMENT
INFLAMMATION

Access to Document

10.1038/s41419-019-1518-0

Cite this

Vig, S., Buitinga, M., Rondas, D., Crevecoeur, I., van Zandvoort, M., Waelkens, E., Eizirik, D. L., Gysemans, C., Baatsen, P., Mathieu, C., & Overbergh, L. (2019). Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells. Cell Death & Disease, 10, 1-13. [309]. https://doi.org/10.1038/s41419-019-1518-0

Vig, Saurabh ; Buitinga, Mijke ; Rondas, Dieter ; Crevecoeur, Inne ; van Zandvoort, Marc ; Waelkens, Etienne ; Eizirik, Decio L. ; Gysemans, Conny ; Baatsen, Pieter ; Mathieu, Chantal ; Overbergh, Lut. / Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells. In: Cell Death & Disease. 2019 ; Vol. 10. pp. 1-13.

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title = "Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells",

keywords = "ENDOPLASMIC-RETICULUM STRESS, COOH-TERMINAL DOMAIN, SURFACE GRP78, MONOCLONAL-ANTIBODY, PROTEIN BIP, CANCER, LIGATION, PROLIFERATION, ESTABLISHMENT, INFLAMMATION",

author = "Saurabh Vig and Mijke Buitinga and Dieter Rondas and Inne Crevecoeur and {van Zandvoort}, Marc and Etienne Waelkens and Eizirik, {Decio L.} and Conny Gysemans and Pieter Baatsen and Chantal Mathieu and Lut Overbergh",

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month = apr,

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doi = "10.1038/s41419-019-1518-0",

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journal = "Cell Death & Disease",

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Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells. / Vig, Saurabh; Buitinga, Mijke; Rondas, Dieter; Crevecoeur, Inne; van Zandvoort, Marc; Waelkens, Etienne; Eizirik, Decio L.; Gysemans, Conny; Baatsen, Pieter; Mathieu, Chantal; Overbergh, Lut.

In: Cell Death & Disease, Vol. 10, 309, 05.04.2019, p. 1-13.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells

AU - Vig, Saurabh

AU - Buitinga, Mijke

AU - Rondas, Dieter

AU - Crevecoeur, Inne

AU - van Zandvoort, Marc

AU - Waelkens, Etienne

AU - Eizirik, Decio L.

AU - Gysemans, Conny

AU - Baatsen, Pieter

AU - Mathieu, Chantal

AU - Overbergh, Lut

PY - 2019/4/5

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KW - COOH-TERMINAL DOMAIN

KW - SURFACE GRP78

KW - MONOCLONAL-ANTIBODY

KW - PROTEIN BIP

KW - CANCER

KW - LIGATION

KW - PROLIFERATION

KW - ESTABLISHMENT

KW - INFLAMMATION

U2 - 10.1038/s41419-019-1518-0

DO - 10.1038/s41419-019-1518-0

M3 - Article

VL - 10

SP - 1

EP - 13

JO - Cell Death & Disease

JF - Cell Death & Disease

SN - 2041-4889

M1 - 309

ER -