Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells

Saurabh Vig, Mijke Buitinga, Dieter Rondas, Inne Crevecoeur, Marc van Zandvoort, Etienne Waelkens, Decio L. Eizirik, Conny Gysemans, Pieter Baatsen, Chantal Mathieu, Lut Overbergh*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number309
Pages (from-to)1-13
Number of pages13
JournalCell Death & Disease
Volume10
DOIs
Publication statusPublished - 5 Apr 2019

Keywords

  • ENDOPLASMIC-RETICULUM STRESS
  • COOH-TERMINAL DOMAIN
  • SURFACE GRP78
  • MONOCLONAL-ANTIBODY
  • PROTEIN BIP
  • CANCER
  • LIGATION
  • PROLIFERATION
  • ESTABLISHMENT
  • INFLAMMATION

Cite this

Vig, S., Buitinga, M., Rondas, D., Crevecoeur, I., van Zandvoort, M., Waelkens, E., Eizirik, D. L., Gysemans, C., Baatsen, P., Mathieu, C., & Overbergh, L. (2019). Cytokine-induced translocation of GRP78 to the plasma membrane triggers a pro-apoptotic feedback loop in pancreatic beta cells. Cell Death & Disease, 10, 1-13. [309]. https://doi.org/10.1038/s41419-019-1518-0