Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis

Anne Kienhuis; Alexa P. Vitins; Jeroen L. A. Pennings; Tessa E. Pronk; Ewoud N. Speksnijder; Marianne Roodbergen; Joost H. M. van Delft; Mirjam Luijten; Leo T. M. van der Ven

doi:10.1016/j.toxlet.2013.06.236

Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis

Anne Kienhuis, Alexa P. Vitins^*, Jeroen L. A. Pennings, Tessa E. Pronk, Ewoud N. Speksnijder, Marianne Roodbergen, Joost H. M. van Delft, Mirjam Luijten, Leo T. M. van der Ven

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	225-236
Journal	Toxicology Letters
Volume	221
Issue number	3
DOIs	https://doi.org/10.1016/j.toxlet.2013.06.236
Publication status	Published - 29 Aug 2013

Keywords

Phenotype-directed gene expression analysis
Hepatotoxicity
Cholestasis
Cyclosporin A
Mouse in vivo
In vitro models

Access to Document

10.1016/j.toxlet.2013.06.236

Cite this

Kienhuis, A., Vitins, A. P., Pennings, J. L. A., Pronk, T. E., Speksnijder, E. N., Roodbergen, M., van Delft, J. H. M., Luijten, M., & van der Ven, L. T. M. (2013). Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis. Toxicology Letters, 221(3), 225-236. https://doi.org/10.1016/j.toxlet.2013.06.236

Kienhuis, Anne ; Vitins, Alexa P. ; Pennings, Jeroen L. A. ; Pronk, Tessa E. ; Speksnijder, Ewoud N. ; Roodbergen, Marianne ; van Delft, Joost H. M. ; Luijten, Mirjam ; van der Ven, Leo T. M. / Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis. In: Toxicology Letters. 2013 ; Vol. 221, No. 3. pp. 225-236.

@article{74074ae8830e45278535bb105522cfba,

title = "Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis",

keywords = "Phenotype-directed gene expression analysis, Hepatotoxicity, Cholestasis, Cyclosporin A, Mouse in vivo, In vitro models",

author = "Anne Kienhuis and Vitins, {Alexa P.} and Pennings, {Jeroen L. A.} and Pronk, {Tessa E.} and Speksnijder, {Ewoud N.} and Marianne Roodbergen and {van Delft}, {Joost H. M.} and Mirjam Luijten and {van der Ven}, {Leo T. M.}",

year = "2013",

month = aug,

day = "29",

doi = "10.1016/j.toxlet.2013.06.236",

language = "English",

volume = "221",

pages = "225--236",

journal = "Toxicology Letters",

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Kienhuis, A, Vitins, AP, Pennings, JLA, Pronk, TE, Speksnijder, EN, Roodbergen, M, van Delft, JHM, Luijten, M & van der Ven, LTM 2013, 'Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis', Toxicology Letters, vol. 221, no. 3, pp. 225-236. https://doi.org/10.1016/j.toxlet.2013.06.236

Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis. / Kienhuis, Anne; Vitins, Alexa P.; Pennings, Jeroen L. A.; Pronk, Tessa E.; Speksnijder, Ewoud N.; Roodbergen, Marianne; van Delft, Joost H. M.; Luijten, Mirjam; van der Ven, Leo T. M.

In: Toxicology Letters, Vol. 221, No. 3, 29.08.2013, p. 225-236.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis

AU - Kienhuis, Anne

AU - Vitins, Alexa P.

AU - Pennings, Jeroen L. A.

AU - Pronk, Tessa E.

AU - Speksnijder, Ewoud N.

AU - Roodbergen, Marianne

AU - van Delft, Joost H. M.

AU - Luijten, Mirjam

AU - van der Ven, Leo T. M.

PY - 2013/8/29

Y1 - 2013/8/29

KW - Phenotype-directed gene expression analysis

KW - Hepatotoxicity

KW - Cholestasis

KW - Cyclosporin A

KW - Mouse in vivo

KW - In vitro models

U2 - 10.1016/j.toxlet.2013.06.236

DO - 10.1016/j.toxlet.2013.06.236

M3 - Article

C2 - 23830897

VL - 221

SP - 225

EP - 236

JO - Toxicology Letters

JF - Toxicology Letters

SN - 0378-4274

IS - 3

ER -