Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis

Anne Kienhuis; Alexa P. Vitins; Jeroen L. A. Pennings; Tessa E. Pronk; Ewoud N. Speksnijder; Marianne Roodbergen; Joost H. M. van Delft; Mirjam Luijten; Leo T. M. van der Ven

doi:10.1016/j.toxlet.2013.06.236

Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis

Anne Kienhuis, Alexa P. Vitins, Jeroen L. A. Pennings, Tessa E. Pronk, Ewoud N. Speksnijder, Marianne Roodbergen, Joost H. M. van Delft, Mirjam Luijten, Leo T. M. van der Ven

Research output: Contribution to journal › Article › Academic › peer-review

10 Citations (Scopus)

Original language	English
Pages (from-to)	225-236
Journal	Toxicology Letters
Volume	221
Issue number	3
DOIs	https://doi.org/10.1016/j.toxlet.2013.06.236
Publication status	Published - 29 Aug 2013

Keywords

Phenotype-directed gene expression analysis
Hepatotoxicity
Cholestasis
Cyclosporin A
Mouse in vivo
In vitro models

Cite this

Kienhuis, A., Vitins, A. P., Pennings, J. L. A., Pronk, T. E., Speksnijder, E. N., Roodbergen, M., van Delft, J. H. M., Luijten, M., & van der Ven, L. T. M. (2013). Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis. Toxicology Letters, 221(3), 225-236. https://doi.org/10.1016/j.toxlet.2013.06.236

Kienhuis, Anne ; Vitins, Alexa P. ; Pennings, Jeroen L. A. ; Pronk, Tessa E. ; Speksnijder, Ewoud N. ; Roodbergen, Marianne ; van Delft, Joost H. M. ; Luijten, Mirjam ; van der Ven, Leo T. M. / Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis. In: Toxicology Letters. 2013 ; Vol. 221, No. 3. pp. 225-236.

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title = "Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis",

keywords = "Phenotype-directed gene expression analysis, Hepatotoxicity, Cholestasis, Cyclosporin A, Mouse in vivo, In vitro models",

author = "Anne Kienhuis and Vitins, {Alexa P.} and Pennings, {Jeroen L. A.} and Pronk, {Tessa E.} and Speksnijder, {Ewoud N.} and Marianne Roodbergen and {van Delft}, {Joost H. M.} and Mirjam Luijten and {van der Ven}, {Leo T. M.}",

year = "2013",

month = aug,

day = "29",

doi = "10.1016/j.toxlet.2013.06.236",

language = "English",

volume = "221",

pages = "225--236",

journal = "Toxicology Letters",

issn = "0378-4274",

publisher = "Elsevier Ireland Ltd",

number = "3",

}

Kienhuis, A, Vitins, AP, Pennings, JLA, Pronk, TE, Speksnijder, EN, Roodbergen, M, van Delft, JHM, Luijten, M & van der Ven, LTM 2013, 'Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis', Toxicology Letters, vol. 221, no. 3, pp. 225-236. https://doi.org/10.1016/j.toxlet.2013.06.236

Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis. / Kienhuis, Anne; Vitins, Alexa P.; Pennings, Jeroen L. A.; Pronk, Tessa E.; Speksnijder, Ewoud N.; Roodbergen, Marianne; van Delft, Joost H. M.; Luijten, Mirjam; van der Ven, Leo T. M.

In: Toxicology Letters, Vol. 221, No. 3, 29.08.2013, p. 225-236.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Cyclosporine A treated in vitro models induce cholestasis response through comparison of phenotype-directed gene expression analysis of in vivo Cyclosporine A-induced cholestasis

AU - Kienhuis, Anne

AU - Vitins, Alexa P.

AU - Pennings, Jeroen L. A.

AU - Pronk, Tessa E.

AU - Speksnijder, Ewoud N.

AU - Roodbergen, Marianne

AU - van Delft, Joost H. M.

AU - Luijten, Mirjam

AU - van der Ven, Leo T. M.

PY - 2013/8/29

Y1 - 2013/8/29

KW - Phenotype-directed gene expression analysis

KW - Hepatotoxicity

KW - Cholestasis

KW - Cyclosporin A

KW - Mouse in vivo

KW - In vitro models

U2 - 10.1016/j.toxlet.2013.06.236

DO - 10.1016/j.toxlet.2013.06.236

M3 - Article

VL - 221

SP - 225

EP - 236

JO - Toxicology Letters

JF - Toxicology Letters

SN - 0378-4274

IS - 3

ER -

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10.1016/j.toxlet.2013.06.236