Cyclic AMP Pathway Suppress Autoimmune Neuroinflammation by Inhibiting Functions of Encephalitogenic CD4 T Cells and Enhancing M2 Macrophage Polarization at the Site of Inflammation

Tatyana Veremeyko, Amanda W. Y. Yung, Marina Dukhinova, Inna S. Kuznetsova, Igor Pomytkin, Alexey Lyundup, Tatyana Strekalova, Natasha S. Barteneva, Eugene D. Ponomarev

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article number50
Number of pages21
JournalFrontiers in Immunology
Volume9
DOIs
Publication statusPublished - 25 Jan 2018

Keywords

  • Th1 cells
  • neuroinflammation
  • Forskolin
  • cAMP
  • microRNA-124
  • macrophage
  • M2 polarization
  • ERK
  • TUMOR-ASSOCIATED MACROPHAGES
  • GENE-EXPRESSION
  • GM-CSF
  • ACTIVATED MACROPHAGES
  • MICROGLIAL CELLS
  • INTERFERON-GAMMA
  • PROTEIN
  • PROLIFERATION
  • CAMP
  • DIFFERENTIATION

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