CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8+ T Cell Recruitment in Human Atherosclerosis

Laura Parma; Nadja Sachs; Nikola Sobczak; Zhaolong Li; Kevin Merchant; Jessica Pauli; Marie A. C. Depuydt; Anouk Wezel; Harm J. Smeets; Ilze Bot; Bram Sluetter; Lars Maegdefessel; Christian Weber; Johan Duchene; Remco T. A. Megens

doi:10.1161/CIRCULATIONAHA.124.072560

CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8+ T Cell Recruitment in Human Atherosclerosis

Laura Parma, Nadja Sachs, Nikola Sobczak, Zhaolong Li, Kevin Merchant, Jessica Pauli, Marie A. C. Depuydt, Anouk Wezel, Harm J. Smeets, Ilze Bot, Bram Sluetter, Lars Maegdefessel, Christian Weber, Johan Duchene, Remco T. A. Megens^*

^*Corresponding author for this work

Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

Original language	English
Pages (from-to)	581-584
Number of pages	4
Journal	Circulation
Volume	151
Issue number	8
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.124.072560
Publication status	Published - 25 Feb 2025

Keywords

atherosclerosis
CD8-positive T-lymphocytes
endothelial cells
microscopy
plaque, atherosclerotic
receptors, chemokine
single-cell gene expression analysis

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10.1161/CIRCULATIONAHA.124.072560

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Parma, L., Sachs, N., Sobczak, N., Li, Z., Merchant, K., Pauli, J., Depuydt, M. A. C., Wezel, A., Smeets, H. J., Bot, I., Sluetter, B., Maegdefessel, L., Weber, C., Duchene, J., & Megens, R. T. A. (2025). CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8+ T Cell Recruitment in Human Atherosclerosis. Circulation, 151(8), 581-584. https://doi.org/10.1161/CIRCULATIONAHA.124.072560

@article{5324801517b5453495ba89bcc75dd81c,

title = "CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8+ T Cell Recruitment in Human Atherosclerosis",

keywords = "atherosclerosis, CD8-positive T-lymphocytes, endothelial cells, microscopy, plaque, atherosclerotic, receptors, chemokine, single-cell gene expression analysis",

author = "Laura Parma and Nadja Sachs and Nikola Sobczak and Zhaolong Li and Kevin Merchant and Jessica Pauli and Depuydt, {Marie A. C.} and Anouk Wezel and Smeets, {Harm J.} and Ilze Bot and Bram Sluetter and Lars Maegdefessel and Christian Weber and Johan Duchene and Megens, {Remco T. A.}",

year = "2025",

month = feb,

day = "25",

doi = "10.1161/CIRCULATIONAHA.124.072560",

language = "English",

volume = "151",

pages = "581--584",

journal = "Circulation",

issn = "0009-7322",

publisher = "Lippincott Williams & Wilkins",

number = "8",

}

Parma, L, Sachs, N, Sobczak, N, Li, Z, Merchant, K, Pauli, J, Depuydt, MAC, Wezel, A, Smeets, HJ, Bot, I, Sluetter, B, Maegdefessel, L, Weber, C, Duchene, J & Megens, RTA 2025, 'CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8+ T Cell Recruitment in Human Atherosclerosis', Circulation, vol. 151, no. 8, pp. 581-584. https://doi.org/10.1161/CIRCULATIONAHA.124.072560

TY - JOUR

T1 - CXCL12 Derived From ACKR1+ Intraplaque Neovessels Mediates CD8+ T Cell Recruitment in Human Atherosclerosis

AU - Parma, Laura

AU - Sachs, Nadja

AU - Sobczak, Nikola

AU - Li, Zhaolong

AU - Merchant, Kevin

AU - Pauli, Jessica

AU - Depuydt, Marie A. C.

AU - Wezel, Anouk

AU - Smeets, Harm J.

AU - Bot, Ilze

AU - Sluetter, Bram

AU - Maegdefessel, Lars

AU - Weber, Christian

AU - Duchene, Johan

AU - Megens, Remco T. A.

PY - 2025/2/25

Y1 - 2025/2/25

KW - atherosclerosis

KW - CD8-positive T-lymphocytes

KW - endothelial cells

KW - microscopy

KW - plaque, atherosclerotic

KW - receptors, chemokine

KW - single-cell gene expression analysis

U2 - 10.1161/CIRCULATIONAHA.124.072560

DO - 10.1161/CIRCULATIONAHA.124.072560

M3 - Comment/Letter to the editor

SN - 0009-7322

VL - 151

SP - 581

EP - 584

JO - Circulation

JF - Circulation

IS - 8

ER -

CXCL12 Derived From ACKR1<SUP>+</SUP> Intraplaque Neovessels Mediates CD8<SUP>+</SUP> T Cell Recruitment in Human Atherosclerosis

Keywords

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