Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells

Timothy N. Perkins; Paul M. Peeters; Catrin Albrecht; Roel P. F. Schins; Mieke A. Dentener; Brooke T. Mossman; Emiel F. M. Wouters; Niki L. Reynaert

doi:10.1016/j.taap.2018.04.011

Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells

Timothy N. Perkins, Paul M. Peeters, Catrin Albrecht, Roel P. F. Schins, Mieke A. Dentener, Brooke T. Mossman, Emiel F. M. Wouters, Niki L. Reynaert^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	43-53
Number of pages	11
Journal	Toxicology and Applied Pharmacology
Volume	348
DOIs	https://doi.org/10.1016/j.taap.2018.04.011
Publication status	Published - 1 Jun 2018

Keywords

Crystalline-silica
Sulfatase-1
Lung
Epithelium
HSPG
Silicosis
FIBROBLAST-GROWTH-FACTOR
IDIOPATHIC PULMONARY-FIBROSIS
IRON PLUS ASCORBATE
HEPARAN-SULFATE
IN-VITRO
SIGNALING PATHWAYS
PROTEOGLYCANS
CANCER
GLYCOSAMINOGLYCANS
INFLAMMATION

Access to Document

10.1016/j.taap.2018.04.011

Cite this

Perkins, T. N., Peeters, P. M., Albrecht, C., Schins, R. P. F., Dentener, M. A., Mossman, B. T., Wouters, E. F. M., & Reynaert, N. L. (2018). Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells. Toxicology and Applied Pharmacology, 348, 43-53. https://doi.org/10.1016/j.taap.2018.04.011

Perkins, Timothy N. ; Peeters, Paul M. ; Albrecht, Catrin ; Schins, Roel P. F. ; Dentener, Mieke A. ; Mossman, Brooke T. ; Wouters, Emiel F. M. ; Reynaert, Niki L. / Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells. In: Toxicology and Applied Pharmacology. 2018 ; Vol. 348. pp. 43-53.

@article{681a305d51e349ae82601313eb2f3ec5,

title = "Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells",

keywords = "Crystalline-silica, Sulfatase-1, Lung, Epithelium, HSPG, Silicosis, FIBROBLAST-GROWTH-FACTOR, IDIOPATHIC PULMONARY-FIBROSIS, IRON PLUS ASCORBATE, HEPARAN-SULFATE, IN-VITRO, SIGNALING PATHWAYS, PROTEOGLYCANS, CANCER, GLYCOSAMINOGLYCANS, INFLAMMATION",

author = "Perkins, {Timothy N.} and Peeters, {Paul M.} and Catrin Albrecht and Schins, {Roel P. F.} and Dentener, {Mieke A.} and Mossman, {Brooke T.} and Wouters, {Emiel F. M.} and Reynaert, {Niki L.}",

year = "2018",

month = jun,

day = "1",

doi = "10.1016/j.taap.2018.04.011",

language = "English",

volume = "348",

pages = "43--53",

journal = "Toxicology and Applied Pharmacology",

issn = "0041-008X",

publisher = "Elsevier Science",

}

Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells. / Perkins, Timothy N.; Peeters, Paul M.; Albrecht, Catrin; Schins, Roel P. F.; Dentener, Mieke A.; Mossman, Brooke T.; Wouters, Emiel F. M.; Reynaert, Niki L.

In: Toxicology and Applied Pharmacology, Vol. 348, 01.06.2018, p. 43-53.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells

AU - Perkins, Timothy N.

AU - Peeters, Paul M.

AU - Albrecht, Catrin

AU - Schins, Roel P. F.

AU - Dentener, Mieke A.

AU - Mossman, Brooke T.

AU - Wouters, Emiel F. M.

AU - Reynaert, Niki L.

PY - 2018/6/1

Y1 - 2018/6/1

KW - Crystalline-silica

KW - Sulfatase-1

KW - Lung

KW - Epithelium

KW - HSPG

KW - Silicosis

KW - FIBROBLAST-GROWTH-FACTOR

KW - IDIOPATHIC PULMONARY-FIBROSIS

KW - IRON PLUS ASCORBATE

KW - HEPARAN-SULFATE

KW - IN-VITRO

KW - SIGNALING PATHWAYS

KW - PROTEOGLYCANS

KW - CANCER

KW - GLYCOSAMINOGLYCANS

KW - INFLAMMATION

U2 - 10.1016/j.taap.2018.04.011

DO - 10.1016/j.taap.2018.04.011

M3 - Article

VL - 348

SP - 43

EP - 53

JO - Toxicology and Applied Pharmacology

JF - Toxicology and Applied Pharmacology

SN - 0041-008X

ER -