Crystalline silica alters Sulfatase-1 expression in rat lungs which influences hyper-proliferative and fibrogenic effects in human lung epithelial cells

Timothy N. Perkins, Paul M. Peeters, Catrin Albrecht, Roel P. F. Schins, Mieke A. Dentener, Brooke T. Mossman, Emiel F. M. Wouters, Niki L. Reynaert*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)43-53
Number of pages11
JournalToxicology and Applied Pharmacology
Volume348
DOIs
Publication statusPublished - 1 Jun 2018

Keywords

  • Crystalline-silica
  • Sulfatase-1
  • Lung
  • Epithelium
  • HSPG
  • Silicosis
  • FIBROBLAST-GROWTH-FACTOR
  • IDIOPATHIC PULMONARY-FIBROSIS
  • IRON PLUS ASCORBATE
  • HEPARAN-SULFATE
  • IN-VITRO
  • SIGNALING PATHWAYS
  • PROTEOGLYCANS
  • CANCER
  • GLYCOSAMINOGLYCANS
  • INFLAMMATION

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