Cost-utility of a cardiovascular prevention program in highly educated adults: Intermediate results of a randomized controlled trial

Nele Jacobs*, Silvia Evers, Andre J. H. A. Ament, Neree Claes

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Objectives: Little is known about the costs and the effects of cardiovascular prevention programs targeted at medical and behavioral risk factors. The aim was to evaluate the cost-utility of a cardiovascular prevention program in a general sample of highly educated adults after 1 year of intervention. Methods: The participants were randomly assigned to intervention (n = 208) and usual care conditions (n = 106). The intervention consisted of medical interventions and optional behavior-change interventions (e.g., a tailored Web site). Cost data were registered from a healthcare perspective, and questionnaires were used to determine effectiveness (e.g., quality-adjusted life-years [QALYs]). A cost-utility analysis and sensitivity analyses using bootstrapping were performed on the intermediate results. Results: When adjusting for baseline utility differences, the incremental cost was (sic)433 and the incremental effectiveness was 0.016 QALYs. The incremental cost-effectiveness ratio was (sic)26,91 0 per QALY. Conclusions: The intervention was cost-effective compared with usual care in this sample of highly educated adults after 1 year of intervention. Increased participation would make this intervention highly cost-effective.
Original languageEnglish
Pages (from-to)11-19
JournalInternational Journal of Technology Assessment in Health Care
Issue number1
Publication statusPublished - Jan 2010


  • Cost-utility
  • Cost-effectiveness
  • Cardiovascular prevention
  • Behavior

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