Cost-Effectiveness of perioperative Vaginally Administered estrogen in postmenopausal women undergoing prolapse surgery (EVA trial): study protocol for a multicenter double-blind randomized placebo-controlled trial

E.V. Vodegel; S.E. Zwolsman; A. Vollebregt; R.G. Duijnhoven; J.E. Bosmans; L. Speksnijder; E.J. Roos; W. Spaans; F. Gerards; A. Adriaanse; F. Vernooij; A.L. Milani; M. Sikkema; M. Weemhoff; M. Mous; A. Damoiseaux; H. van Dongen; M. v d Ploeg; J. Veen; G. van de Pol; B. Broekman; P. Steures; F. Tjin-Asjoe; J. van der Stege; R. Mouw; C.H. van der Vaart; J.P.W.R. Roovers

doi:10.1186/s12905-021-01587-9

Cost-Effectiveness of perioperative Vaginally Administered estrogen in postmenopausal women undergoing prolapse surgery (EVA trial): study protocol for a multicenter double-blind randomized placebo-controlled trial

E.V. Vodegel^*, S.E. Zwolsman, A. Vollebregt, R.G. Duijnhoven, J.E. Bosmans, L. Speksnijder, E.J. Roos, W. Spaans, F. Gerards, A. Adriaanse, F. Vernooij, A.L. Milani, M. Sikkema, M. Weemhoff, M. Mous, A. Damoiseaux, H. van Dongen, M. v d Ploeg, J. Veen, G. van de PolB. Broekman, P. Steures, F. Tjin-Asjoe, J. van der Stege, R. Mouw, C.H. van der Vaart, J.P.W.R. Roovers

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Article number	439
Number of pages	10
Journal	BMC Women's Health
Volume	21
Issue number	1
DOIs	https://doi.org/10.1186/s12905-021-01587-9
Publication status	Published - 31 Dec 2021

Keywords

Pelvic organ prolapse
Vaginal estrogen therapy
Postmenopausal
Wound healing
Pelvic reconstructive surgery
Recurrence
Cost-effectiveness
PELVIC ORGAN PROLAPSE
LOCAL ESTROGEN
LIFETIME RISK
ESTRADIOL
QUESTIONNAIRE
VALIDATION
RECURRENCE
OUTCOMES
SUPPORT
ATROPHY

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Vodegel, E. V., Zwolsman, S. E., Vollebregt, A., Duijnhoven, R. G., Bosmans, J. E., Speksnijder, L., Roos, E. J., Spaans, W., Gerards, F., Adriaanse, A., Vernooij, F., Milani, A. L., Sikkema, M., Weemhoff, M., Mous, M., Damoiseaux, A., van Dongen, H., v d Ploeg, M., Veen, J., ... Roovers, J. P. W. R. (2021). Cost-Effectiveness of perioperative Vaginally Administered estrogen in postmenopausal women undergoing prolapse surgery (EVA trial): study protocol for a multicenter double-blind randomized placebo-controlled trial. BMC Women's Health, 21(1), [439]. https://doi.org/10.1186/s12905-021-01587-9

Vodegel, E.V. ; Zwolsman, S.E. ; Vollebregt, A. ; Duijnhoven, R.G. ; Bosmans, J.E. ; Speksnijder, L. ; Roos, E.J. ; Spaans, W. ; Gerards, F. ; Adriaanse, A. ; Vernooij, F. ; Milani, A.L. ; Sikkema, M. ; Weemhoff, M. ; Mous, M. ; Damoiseaux, A. ; van Dongen, H. ; v d Ploeg, M. ; Veen, J. ; van de Pol, G. ; Broekman, B. ; Steures, P. ; Tjin-Asjoe, F. ; van der Stege, J. ; Mouw, R. ; van der Vaart, C.H. ; Roovers, J.P.W.R. / Cost-Effectiveness of perioperative Vaginally Administered estrogen in postmenopausal women undergoing prolapse surgery (EVA trial): study protocol for a multicenter double-blind randomized placebo-controlled trial. In: BMC Women's Health. 2021 ; Vol. 21, No. 1.

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keywords = "Pelvic organ prolapse, Vaginal estrogen therapy, Postmenopausal, Wound healing, Pelvic reconstructive surgery, Recurrence, Cost-effectiveness, PELVIC ORGAN PROLAPSE, LOCAL ESTROGEN, LIFETIME RISK, ESTRADIOL, QUESTIONNAIRE, VALIDATION, RECURRENCE, OUTCOMES, SUPPORT, ATROPHY",

author = "E.V. Vodegel and S.E. Zwolsman and A. Vollebregt and R.G. Duijnhoven and J.E. Bosmans and L. Speksnijder and E.J. Roos and W. Spaans and F. Gerards and A. Adriaanse and F. Vernooij and A.L. Milani and M. Sikkema and M. Weemhoff and M. Mous and A. Damoiseaux and {van Dongen}, H. and {v d Ploeg}, M. and J. Veen and {van de Pol}, G. and B. Broekman and P. Steures and F. Tjin-Asjoe and {van der Stege}, J. and R. Mouw and {van der Vaart}, C.H. and J.P.W.R. Roovers",

year = "2021",

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doi = "10.1186/s12905-021-01587-9",

language = "English",

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Vodegel, EV, Zwolsman, SE, Vollebregt, A, Duijnhoven, RG, Bosmans, JE, Speksnijder, L, Roos, EJ, Spaans, W, Gerards, F, Adriaanse, A, Vernooij, F, Milani, AL, Sikkema, M, Weemhoff, M, Mous, M, Damoiseaux, A, van Dongen, H, v d Ploeg, M, Veen, J, van de Pol, G, Broekman, B, Steures, P, Tjin-Asjoe, F, van der Stege, J, Mouw, R, van der Vaart, CH & Roovers, JPWR 2021, 'Cost-Effectiveness of perioperative Vaginally Administered estrogen in postmenopausal women undergoing prolapse surgery (EVA trial): study protocol for a multicenter double-blind randomized placebo-controlled trial', BMC Women's Health, vol. 21, no. 1, 439. https://doi.org/10.1186/s12905-021-01587-9

Cost-Effectiveness of perioperative Vaginally Administered estrogen in postmenopausal women undergoing prolapse surgery (EVA trial): study protocol for a multicenter double-blind randomized placebo-controlled trial. / Vodegel, E.V.; Zwolsman, S.E.; Vollebregt, A.; Duijnhoven, R.G.; Bosmans, J.E.; Speksnijder, L.; Roos, E.J.; Spaans, W.; Gerards, F.; Adriaanse, A.; Vernooij, F.; Milani, A.L.; Sikkema, M.; Weemhoff, M.; Mous, M.; Damoiseaux, A.; van Dongen, H.; v d Ploeg, M.; Veen, J.; van de Pol, G.; Broekman, B.; Steures, P.; Tjin-Asjoe, F.; van der Stege, J.; Mouw, R.; van der Vaart, C.H.; Roovers, J.P.W.R.

In: BMC Women's Health, Vol. 21, No. 1, 439, 31.12.2021.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Cost-Effectiveness of perioperative Vaginally Administered estrogen in postmenopausal women undergoing prolapse surgery (EVA trial): study protocol for a multicenter double-blind randomized placebo-controlled trial

AU - Vodegel, E.V.

AU - Zwolsman, S.E.

AU - Vollebregt, A.

AU - Duijnhoven, R.G.

AU - Bosmans, J.E.

AU - Speksnijder, L.

AU - Roos, E.J.

AU - Spaans, W.

AU - Gerards, F.

AU - Adriaanse, A.

AU - Vernooij, F.

AU - Milani, A.L.

AU - Sikkema, M.

AU - Weemhoff, M.

AU - Mous, M.

AU - Damoiseaux, A.

AU - van Dongen, H.

AU - v d Ploeg, M.

AU - Veen, J.

AU - van de Pol, G.

AU - Broekman, B.

AU - Steures, P.

AU - Tjin-Asjoe, F.

AU - van der Stege, J.

AU - Mouw, R.

AU - van der Vaart, C.H.

AU - Roovers, J.P.W.R.

PY - 2021/12/31

Y1 - 2021/12/31

KW - Pelvic organ prolapse

KW - Vaginal estrogen therapy

KW - Postmenopausal

KW - Wound healing

KW - Pelvic reconstructive surgery

KW - Recurrence

KW - Cost-effectiveness

KW - PELVIC ORGAN PROLAPSE

KW - LOCAL ESTROGEN

KW - LIFETIME RISK

KW - ESTRADIOL

KW - QUESTIONNAIRE

KW - VALIDATION

KW - RECURRENCE

KW - OUTCOMES

KW - SUPPORT

KW - ATROPHY

U2 - 10.1186/s12905-021-01587-9

DO - 10.1186/s12905-021-01587-9

M3 - Article

C2 - 34972504

VL - 21

JO - BMC Women's Health

JF - BMC Women's Health

SN - 1472-6874

IS - 1

M1 - 439

ER -

Vodegel EV, Zwolsman SE, Vollebregt A, Duijnhoven RG, Bosmans JE, Speksnijder L et al. Cost-Effectiveness of perioperative Vaginally Administered estrogen in postmenopausal women undergoing prolapse surgery (EVA trial): study protocol for a multicenter double-blind randomized placebo-controlled trial. BMC Women's Health. 2021 Dec 31;21(1). 439. https://doi.org/10.1186/s12905-021-01587-9