Abstract
Background: This study aims to present an overview and critical appraisal of all previous studies comparing costs and outcomes of the different modes of fixation in total hip arthroplasty (THA). A secondary aim is to provide conclusions regarding the most cost-effective mode of implant fixation per gender and age-specific population in THA, based on high quality studies.Methods: A systematic search was conducted to identify cost-effectiveness analyses (CEAs) comparing different modes of implant fixation in THA. Analysis of results was done with solely CEAs that had a high methodological quality.Results: A total of 12 relevant studies were identified and presented, of which 5 were considered to have the methodological rigor for inclusion in the analysis of results. These studies found that either cemented or hybrid fixation was the most cost-effective implant fixation mode for most age- and gender-specific subgroups.Conclusion: Currently available well performed CEAs generally support the use of cemented and hybrid fixation for all age-groups relevant for THA and both genders. However, these findings were mainly based on a single database and depended on assumptions made in the studies' methodology. Issues discussed in this paper have to be considered and future work is needed.
Original language | English |
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Pages (from-to) | 579-593 |
Number of pages | 15 |
Journal | Expert Review of Pharmacoeconomics & Outcomes Research |
Volume | 21 |
Issue number | 4 |
DOIs | |
Publication status | Published - 4 Jul 2021 |
Keywords
- total hip arthroplasty
- implant fixation
- cost-effectiveness
- cemented
- cementless
- hybrid
- reverse hybrid
- REPLACEMENT
- IMPLANT
- METAANALYSIS
- SURVIVAL
- QUALITY
- TRENDS
- WORK
- AGE