Corticosteroid enhances epithelial barrier function in intestinal organoids derived from patients with Crohn's disease

Keyphrases

• Crohn's Disease 100%
• Corticosteroids 100%
• Intestinal Organoids 100%
• Prednisolone 100%
• Epithelial Barrier Function 100%
• Epithelial Barrier 33%
• Western Blot 22%
• E-cadherin 22%
• Interleukin-1β 11%
• Tumor Necrosis Factor-α 11%
• Quantitative PCR 11%
• Severe Disease 11%
• Signaling Pathway 11%
• Intestinal Permeability 11%
• Intestinal Barrier 11%
• Disease Activity 11%
• Interferon-γ 11%
• Barrier Dysfunction 11%
• Confocal Microscopy 11%
• Colon Biopsy 11%
• Molecular Events 11%
• Clinical Efficacy 11%
• Preventive Effect 11%
• Immunofluorescence Staining 11%
• Patient-derived 11%
• Pre-incubation 11%
• Moderate Disease 11%
• Mifepristone 11%
• Organoids 11%
• Epithelial Permeability 11%
• Inflammatory Microenvironment 11%
• Organoid Culture 11%
• STAT1 Phosphorylation 11%
• Gamma 1 11%

INIS

• diseases 100%
• corticosteroids 100%
• patients 100%
• barriers 100%
• organoids 100%
• prednisolone 100%
• cytokines 55%
• mixtures 33%
• permeability 22%
• levels 11%
• reduction 11%
• biopsy 11%
• microscopy 11%
• inflammation 11%
• phosphorylation 11%
• mimic 11%
• colon 11%
• pcr 11%
• compartments 11%
• luminal 11%
• incubation 11%
• restoration 11%

Immunology and Microbiology

• Crohn's Disease 100%
• Prednisolone 100%
• Organoid 100%
• Cytokine 55%
• Western Blot 22%
• STAT1 22%
• Cadherin 22%
• Colon 11%
• Quantitative Reverse Transcription Polymerase Chain Reaction 11%
• Tumor Necrosis Factor Alpha 11%
• Immunofluorescence 11%
• Interleukin-1 11%
• Confocal Microscopy 11%