Correlation of tumor size with other prognostic factors in uterine serous carcinoma: A large multi-institutional study

Ira S. Winer; Haider S. Mahdi; Sudeshna Bandyopadhyay; Assaad Semaan; K. K. Van de Vijver; Marisa R. Nucci; F. Abdul-Karim; Yaser Hussein; F. Qureshi; Kinda Hayek; Baraa Alosh; D. Schulz; Michele L. Cote; Adnan R. Munkarah; Richard Morris; Esther Oliva; Rouba Ali-Fehmi

doi:10.1016/j.ygyno.2012.10.027

Correlation of tumor size with other prognostic factors in uterine serous carcinoma: A large multi-institutional study

Ira S. Winer, Haider S. Mahdi, Sudeshna Bandyopadhyay, Assaad Semaan, K. K. Van de Vijver, Marisa R. Nucci, F. Abdul-Karim, Yaser Hussein, F. Qureshi, Kinda Hayek, Baraa Alosh, D. Schulz, Michele L. Cote, Adnan R. Munkarah, Richard Morris, Esther Oliva, Rouba Ali-Fehmi^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Uterine serous carcinoma (USC) constitutes 10% of uterine cancers but ~40% of deaths. Tumor size is a known prognostic factor in other solid tumors. In endometriod cancers it is one element used to identify the need for complete staging, while its significance in USC is debated. Therefore tumor size was examined as an independent prognostic factor.Clinical and pathologic variables were recorded for 236 institutional patients, and those patients in the SEER database with USC. Chi-square and Fisher exact t-tests were utilized and survival data generated via Kaplan-Meier method; multivariate analysis was performed via cox-regression.The patients' mean age was 67.2 years (range 40-91). Survival ranged from 0 to 184 months (mean 42.8). We used a tumor size cut-off of 1cm and noted significant associations with myometrial invasion (p

Original language	English
Pages (from-to)	316-321
Journal	Gynecologic Oncology
Volume	128
Issue number	2
DOIs	https://doi.org/10.1016/j.ygyno.2012.10.027
Publication status	Published - Feb 2013

Keywords

Uterine serous carcinoma (USC)
Staging
Tumor size
Prognostic factors

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10.1016/j.ygyno.2012.10.027

Cite this

Winer, I. S., Mahdi, H. S., Bandyopadhyay, S., Semaan, A., Van de Vijver, K. K., Nucci, M. R., Abdul-Karim, F., Hussein, Y., Qureshi, F., Hayek, K., Alosh, B., Schulz, D., Cote, M. L., Munkarah, A. R., Morris, R., Oliva, E., & Ali-Fehmi, R. (2013). Correlation of tumor size with other prognostic factors in uterine serous carcinoma: A large multi-institutional study. Gynecologic Oncology, 128(2), 316-321. https://doi.org/10.1016/j.ygyno.2012.10.027

@article{9d229f818d334ee78e7b3fdf18b9d355,

title = "Correlation of tumor size with other prognostic factors in uterine serous carcinoma: A large multi-institutional study",

abstract = "Uterine serous carcinoma (USC) constitutes 10% of uterine cancers but ~40% of deaths. Tumor size is a known prognostic factor in other solid tumors. In endometriod cancers it is one element used to identify the need for complete staging, while its significance in USC is debated. Therefore tumor size was examined as an independent prognostic factor.Clinical and pathologic variables were recorded for 236 institutional patients, and those patients in the SEER database with USC. Chi-square and Fisher exact t-tests were utilized and survival data generated via Kaplan-Meier method; multivariate analysis was performed via cox-regression.The patients' mean age was 67.2 years (range 40-91). Survival ranged from 0 to 184 months (mean 42.8). We used a tumor size cut-off of 1cm and noted significant associations with myometrial invasion (p",

keywords = "Uterine serous carcinoma (USC), Staging, Tumor size, Prognostic factors",

author = "Winer, {Ira S.} and Mahdi, {Haider S.} and Sudeshna Bandyopadhyay and Assaad Semaan and {Van de Vijver}, {K. K.} and Nucci, {Marisa R.} and F. Abdul-Karim and Yaser Hussein and F. Qureshi and Kinda Hayek and Baraa Alosh and D. Schulz and Cote, {Michele L.} and Munkarah, {Adnan R.} and Richard Morris and Esther Oliva and Rouba Ali-Fehmi",

year = "2013",

month = feb,

doi = "10.1016/j.ygyno.2012.10.027",

language = "English",

volume = "128",

pages = "316--321",

journal = "Gynecologic Oncology",

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number = "2",

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Winer, IS, Mahdi, HS, Bandyopadhyay, S, Semaan, A, Van de Vijver, KK, Nucci, MR, Abdul-Karim, F, Hussein, Y, Qureshi, F, Hayek, K, Alosh, B, Schulz, D, Cote, ML, Munkarah, AR, Morris, R, Oliva, E & Ali-Fehmi, R 2013, 'Correlation of tumor size with other prognostic factors in uterine serous carcinoma: A large multi-institutional study', Gynecologic Oncology, vol. 128, no. 2, pp. 316-321. https://doi.org/10.1016/j.ygyno.2012.10.027

TY - JOUR

T1 - Correlation of tumor size with other prognostic factors in uterine serous carcinoma: A large multi-institutional study

AU - Winer, Ira S.

AU - Mahdi, Haider S.

AU - Bandyopadhyay, Sudeshna

AU - Semaan, Assaad

AU - Van de Vijver, K. K.

AU - Nucci, Marisa R.

AU - Abdul-Karim, F.

AU - Hussein, Yaser

AU - Qureshi, F.

AU - Hayek, Kinda

AU - Alosh, Baraa

AU - Schulz, D.

AU - Cote, Michele L.

AU - Munkarah, Adnan R.

AU - Morris, Richard

AU - Oliva, Esther

AU - Ali-Fehmi, Rouba

PY - 2013/2

Y1 - 2013/2

N2 - Uterine serous carcinoma (USC) constitutes 10% of uterine cancers but ~40% of deaths. Tumor size is a known prognostic factor in other solid tumors. In endometriod cancers it is one element used to identify the need for complete staging, while its significance in USC is debated. Therefore tumor size was examined as an independent prognostic factor.Clinical and pathologic variables were recorded for 236 institutional patients, and those patients in the SEER database with USC. Chi-square and Fisher exact t-tests were utilized and survival data generated via Kaplan-Meier method; multivariate analysis was performed via cox-regression.The patients' mean age was 67.2 years (range 40-91). Survival ranged from 0 to 184 months (mean 42.8). We used a tumor size cut-off of 1cm and noted significant associations with myometrial invasion (p

AB - Uterine serous carcinoma (USC) constitutes 10% of uterine cancers but ~40% of deaths. Tumor size is a known prognostic factor in other solid tumors. In endometriod cancers it is one element used to identify the need for complete staging, while its significance in USC is debated. Therefore tumor size was examined as an independent prognostic factor.Clinical and pathologic variables were recorded for 236 institutional patients, and those patients in the SEER database with USC. Chi-square and Fisher exact t-tests were utilized and survival data generated via Kaplan-Meier method; multivariate analysis was performed via cox-regression.The patients' mean age was 67.2 years (range 40-91). Survival ranged from 0 to 184 months (mean 42.8). We used a tumor size cut-off of 1cm and noted significant associations with myometrial invasion (p

KW - Uterine serous carcinoma (USC)

KW - Staging

KW - Tumor size

KW - Prognostic factors

U2 - 10.1016/j.ygyno.2012.10.027

DO - 10.1016/j.ygyno.2012.10.027

M3 - Article

C2 - 23138135

SN - 0090-8258

VL - 128

SP - 316

EP - 321

JO - Gynecologic Oncology

JF - Gynecologic Oncology

IS - 2

ER -