Introduction Diabetic neuropathy can be diagnosed and assessed using a number of techniques including corneal confocal microscopy (CCM).
Research design and methods We have undertaken quantitative sensory testing, nerve conduction studies and CCM in 143 patients with type 1 and type 2 diabetes without neuropathy (n=51), mild neuropathy (n=47) and moderate to severe neuropathy (n=45) and age-matched controls (n=30).
Results Vibration perception threshold (p
Conclusion This study shows that CCM identifies early and progressive corneal nerve loss at the inferior whorl and central cornea and has comparable utility with quantitative sensory testing and nerve conduction in the diagnosis of diabetic neuropathy.
- diabetic neuropathies
- diabetes complications
- SMALL-FIBER NEUROPATHY
- SENSORIMOTOR POLYNEUROPATHY