Contemporary management of patients with structural heart disease undergoing catheter ablation of ventricular arrhythmias

This thesis investigated how patients with structural heart disease, who often suffer from dangerous heart rhythm disturbances called ventricular arrhythmias, can best be treated with catheter ablation. This minimally invasive procedure uses radiofrequency or other energy sources to interrupt abnormal electrical signals in the heart. The research analyzed data from hundreds of procedures performed at a high-volume center, including epicardial and repeat ablations. It examined the safety and effectiveness of ablation, the role of modern imaging, and the management of complications. Special attention was given to gender differences, patients with advanced heart failure, and those supported by ventricular assist devices. The findings show that while ablation is an effective treatment for many, risks remain and outcomes differ depending on the underlying heart disease. The work emphasizes careful patient selection, improved imaging integration, and multidisciplinary care to optimize treatment safety, effectiveness, and patient quality of life.