Connecting the dots : new perspectives on stress and psychosis

J.J.E. Lataster

Research output: ThesisDoctoral ThesisInternal

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Abstract


Psychotic disorders, among which schizophrenia, belong to the most paralyzing and elusive psychiatric diseases. Although it is assumed that stress plays an important role in the development of psychotic experiences, by far not everyone becomes psychotic after a stressful event. This dissertation studies why one person does and the other doesn’t react psychotically to stress – which mechanisms are involved there? One of the conclusions is that dopamine stress handling in the brains of persons with psychotic vulnerability shows defects – a defect that is partly ‘family-related’, but on the other hand may be stirred up by repeated exposure to radical stressful events.
Original languageEnglish
QualificationDoctor of Philosophy
Awarding Institution
  • Maastricht University
Supervisors/Advisors
  • Myin-Germeys, I., Supervisor, External person
Award date27 Jan 2012
Place of PublicationMaastricht
Publisher
Print ISBNs9789085707981
Publication statusPublished - 1 Jan 2012

Keywords

  • psychotic disorder
  • schizophrenia
  • stress
  • dopamine

Cite this

Lataster, J. J. E. (2012). Connecting the dots : new perspectives on stress and psychosis. Maastricht University.