Conducting radiogenomic research - Do not forget careful consideration of the clinical data

Christian Nicolaj Andreassen*, Gillian C. Barnett, Johannes A. Langendijk, Jan Alsner, Dirk De Ruysscher, Mechtild Krause, Soren M. Bentzen, Joanne S. Haviland, Clare Griffin, Philip Poortmans, John R. Yarnold

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

26 Citations (Web of Science)

Abstract

The field of radiogenomics has evolved substantially over the last few years. Cooperative research groups have been established and high throughput genotyping has become increasingly feasible and affordable. Nevertheless, a number of clinical and dosimetric issues need to be carefully considered in order to fully exploit these new possibilities.
Original languageEnglish
Pages (from-to)337-340
JournalRadiotherapy and Oncology
Volume105
Issue number3
DOIs
Publication statusPublished - Dec 2012

Keywords

  • Normal tissue radiosensitivity
  • Predictive markers
  • Single nucleotide polymorphisms

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