Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort

Undine Rulle; Zoi Tsourti; Ruben Casanova; Karl-Friedrich Deml; Eric Verbeken; Erik Thunnissen; Arne Warth; Richard Cheney; Aleksandra Sejda; Ernst Jan Speel; Line Bille Madsen; Daisuke Nonaka; Atilio Navarro; Irene Sansano; Antonio Marchetti; Stephen P. Finn; Kim Monkhorst; Keith M. Kerr; Martina Haberecker; Chengguang Wu; Panagiota Zygoura; Roswitha Kammler; Thomas Geiger; Steven Gendreau; Katja Schulze; Bart Vrugt; Peter Wild; Holger Moch; Walter Weder; Ata Tuna Ciftlik; Urania Dafni; Solange Peters; Lukas Bubendorf; Rolf A. Stahel; Alex Soltermann

doi:10.1016/j.jtho.2018.08.2034

Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort

Undine Rulle, Zoi Tsourti, Ruben Casanova, Karl-Friedrich Deml, Eric Verbeken, Erik Thunnissen, Arne Warth, Richard Cheney, Aleksandra Sejda, Ernst Jan Speel, Line Bille Madsen, Daisuke Nonaka, Atilio Navarro, Irene Sansano, Antonio Marchetti, Stephen P. Finn, Kim Monkhorst, Keith M. Kerr, Martina Haberecker, Chengguang WuPanagiota Zygoura, Roswitha Kammler, Thomas Geiger, Steven Gendreau, Katja Schulze, Bart Vrugt, Peter Wild, Holger Moch, Walter Weder, Ata Tuna Ciftlik, Urania Dafni, Solange Peters, Lukas Bubendorf, Rolf A. Stahel, Alex Soltermann^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Web of Science)

Original language	English
Pages (from-to)	1851-1863
Number of pages	13
Journal	Journal of Thoracic Oncology
Volume	13
Issue number	12
DOIs	https://doi.org/10.1016/j.jtho.2018.08.2034
Publication status	Published - 1 Dec 2018

Keywords

PTEN
NSCLC
External quality assessment
Computer-based intensity measurement
Immunohistochemistry
SQUAMOUS-CELL CARCINOMA
LUNG-CANCER
ENDOMETRIAL CARCINOMA
PTEN EXPRESSION
PROSTATE-CANCER
HER2 IMMUNOHISTOCHEMISTRY
ANALYTIC VALIDATION
TISSUE MICROARRAY
BREAST
DEREGULATION

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10.1016/j.jtho.2018.08.2034

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Rulle, U., Tsourti, Z., Casanova, R., Deml, K-F., Verbeken, E., Thunnissen, E., Warth, A., Cheney, R., Sejda, A., Speel, E. J., Madsen, L. B., Nonaka, D., Navarro, A., Sansano, I., Marchetti, A., Finn, S. P., Monkhorst, K., Kerr, K. M., Haberecker, M., ... Soltermann, A. (2018). Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort. Journal of Thoracic Oncology, 13(12), 1851-1863. https://doi.org/10.1016/j.jtho.2018.08.2034

Rulle, Undine ; Tsourti, Zoi ; Casanova, Ruben ; Deml, Karl-Friedrich ; Verbeken, Eric ; Thunnissen, Erik ; Warth, Arne ; Cheney, Richard ; Sejda, Aleksandra ; Speel, Ernst Jan ; Madsen, Line Bille ; Nonaka, Daisuke ; Navarro, Atilio ; Sansano, Irene ; Marchetti, Antonio ; Finn, Stephen P. ; Monkhorst, Kim ; Kerr, Keith M. ; Haberecker, Martina ; Wu, Chengguang ; Zygoura, Panagiota ; Kammler, Roswitha ; Geiger, Thomas ; Gendreau, Steven ; Schulze, Katja ; Vrugt, Bart ; Wild, Peter ; Moch, Holger ; Weder, Walter ; Ciftlik, Ata Tuna ; Dafni, Urania ; Peters, Solange ; Bubendorf, Lukas ; Stahel, Rolf A. ; Soltermann, Alex. / Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort. In: Journal of Thoracic Oncology. 2018 ; Vol. 13, No. 12. pp. 1851-1863.

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title = "Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort",

keywords = "PTEN, NSCLC, External quality assessment, Computer-based intensity measurement, Immunohistochemistry, SQUAMOUS-CELL CARCINOMA, LUNG-CANCER, ENDOMETRIAL CARCINOMA, PTEN EXPRESSION, PROSTATE-CANCER, HER2 IMMUNOHISTOCHEMISTRY, ANALYTIC VALIDATION, TISSUE MICROARRAY, BREAST, DEREGULATION",

author = "Undine Rulle and Zoi Tsourti and Ruben Casanova and Karl-Friedrich Deml and Eric Verbeken and Erik Thunnissen and Arne Warth and Richard Cheney and Aleksandra Sejda and Speel, {Ernst Jan} and Madsen, {Line Bille} and Daisuke Nonaka and Atilio Navarro and Irene Sansano and Antonio Marchetti and Finn, {Stephen P.} and Kim Monkhorst and Kerr, {Keith M.} and Martina Haberecker and Chengguang Wu and Panagiota Zygoura and Roswitha Kammler and Thomas Geiger and Steven Gendreau and Katja Schulze and Bart Vrugt and Peter Wild and Holger Moch and Walter Weder and Ciftlik, {Ata Tuna} and Urania Dafni and Solange Peters and Lukas Bubendorf and Stahel, {Rolf A.} and Alex Soltermann",

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month = dec,

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doi = "10.1016/j.jtho.2018.08.2034",

language = "English",

volume = "13",

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journal = "Journal of Thoracic Oncology",

issn = "1556-0864",

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Rulle, U, Tsourti, Z, Casanova, R, Deml, K-F, Verbeken, E, Thunnissen, E, Warth, A, Cheney, R, Sejda, A, Speel, EJ, Madsen, LB, Nonaka, D, Navarro, A, Sansano, I, Marchetti, A, Finn, SP, Monkhorst, K, Kerr, KM, Haberecker, M, Wu, C, Zygoura, P, Kammler, R, Geiger, T, Gendreau, S, Schulze, K, Vrugt, B, Wild, P, Moch, H, Weder, W, Ciftlik, AT, Dafni, U, Peters, S, Bubendorf, L, Stahel, RA & Soltermann, A 2018, 'Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort', Journal of Thoracic Oncology, vol. 13, no. 12, pp. 1851-1863. https://doi.org/10.1016/j.jtho.2018.08.2034

Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort. / Rulle, Undine; Tsourti, Zoi; Casanova, Ruben; Deml, Karl-Friedrich; Verbeken, Eric; Thunnissen, Erik; Warth, Arne; Cheney, Richard; Sejda, Aleksandra; Speel, Ernst Jan; Madsen, Line Bille; Nonaka, Daisuke; Navarro, Atilio; Sansano, Irene; Marchetti, Antonio; Finn, Stephen P.; Monkhorst, Kim; Kerr, Keith M.; Haberecker, Martina; Wu, Chengguang; Zygoura, Panagiota; Kammler, Roswitha; Geiger, Thomas; Gendreau, Steven; Schulze, Katja; Vrugt, Bart; Wild, Peter; Moch, Holger; Weder, Walter; Ciftlik, Ata Tuna; Dafni, Urania; Peters, Solange; Bubendorf, Lukas; Stahel, Rolf A.; Soltermann, Alex.

In: Journal of Thoracic Oncology, Vol. 13, No. 12, 01.12.2018, p. 1851-1863.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort

AU - Rulle, Undine

AU - Tsourti, Zoi

AU - Casanova, Ruben

AU - Deml, Karl-Friedrich

AU - Verbeken, Eric

AU - Thunnissen, Erik

AU - Warth, Arne

AU - Cheney, Richard

AU - Sejda, Aleksandra

AU - Speel, Ernst Jan

AU - Madsen, Line Bille

AU - Nonaka, Daisuke

AU - Navarro, Atilio

AU - Sansano, Irene

AU - Marchetti, Antonio

AU - Finn, Stephen P.

AU - Monkhorst, Kim

AU - Kerr, Keith M.

AU - Haberecker, Martina

AU - Wu, Chengguang

AU - Zygoura, Panagiota

AU - Kammler, Roswitha

AU - Geiger, Thomas

AU - Gendreau, Steven

AU - Schulze, Katja

AU - Vrugt, Bart

AU - Wild, Peter

AU - Moch, Holger

AU - Weder, Walter

AU - Ciftlik, Ata Tuna

AU - Dafni, Urania

AU - Peters, Solange

AU - Bubendorf, Lukas

AU - Stahel, Rolf A.

AU - Soltermann, Alex

PY - 2018/12/1

Y1 - 2018/12/1

KW - PTEN

KW - NSCLC

KW - External quality assessment

KW - Computer-based intensity measurement

KW - Immunohistochemistry

KW - SQUAMOUS-CELL CARCINOMA

KW - LUNG-CANCER

KW - ENDOMETRIAL CARCINOMA

KW - PTEN EXPRESSION

KW - PROSTATE-CANCER

KW - HER2 IMMUNOHISTOCHEMISTRY

KW - ANALYTIC VALIDATION

KW - TISSUE MICROARRAY

KW - BREAST

KW - DEREGULATION

U2 - 10.1016/j.jtho.2018.08.2034

DO - 10.1016/j.jtho.2018.08.2034

M3 - Article

C2 - 30240851

VL - 13

SP - 1851

EP - 1863

JO - Journal of Thoracic Oncology

JF - Journal of Thoracic Oncology

SN - 1556-0864

IS - 12

ER -

Rulle U, Tsourti Z, Casanova R, Deml K-F, Verbeken E, Thunnissen E et al. Computer-Based Intensity Measurement Assists Pathologists in Scoring Phosphatase and Tensin Homolog Immunohistochemistry - Clinical Associations in NSCLC Patients of the European Thoracic Oncology Platform Lungscape Cohort. Journal of Thoracic Oncology. 2018 Dec 1;13(12):1851-1863. https://doi.org/10.1016/j.jtho.2018.08.2034