Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options-a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference

Paulus Kirchhof; Gregory Y. H. Lip; Isabelle C. Van Gelder; Jeroen Bax; Elaine Hylek; Stefan Kaab; Ulrich Schotten; Karl Wegscheider; Giuseppe Boriani; Axel Brandes; Michael D. Ezekowitz; Hans-Christoph Diener; Laurent Haegeli; Hein Heidbuchel; Deirdre A. Lane; Luis Mont; Stephan Willems; Paul Dorian; Maria Aunes-Jansson; Carina Blomstrom-Lundqvist; Maria Borentain; Stefanie Breitenstein; Martina Brueckmann; Nilo Cater; Andreas Clemens; Dobromir Dobrev; Sergio Dubner; Nils G. Edvardsson; Leif Friberg; Andreas Goette; Michele Gulizia; Robert Hatala; Jenny Horwood; Lukas Szumowski; Lukas Kappenberger; Josef Kautzner; Angelika Leute; Trudie Lobban; Ralf Meyer; Jay Millerhagen; John Morgan; Felix Muenzel; Michael Nabauer; Christoph Baertels; Michael Oeff; Dieter Paar; Juergen Polifka; Ursula Ravens; Ludger Rosin; Wim Stegink; Gerhard Steinbeck; Panos Vardas; Alphons Vincent; Maureen Walter; Guenter Breithardt; A. John Camm

doi:10.1093/europace/eur241

Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options-a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference

Paulus Kirchhof^*, Gregory Y. H. Lip, Isabelle C. Van Gelder, Jeroen Bax, Elaine Hylek, Stefan Kaab, Ulrich Schotten, Karl Wegscheider, Giuseppe Boriani, Axel Brandes, Michael D. Ezekowitz, Hans-Christoph Diener, Laurent Haegeli, Hein Heidbuchel, Deirdre A. Lane, Luis Mont, Stephan Willems, Paul Dorian, Maria Aunes-Jansson, Carina Blomstrom-LundqvistMaria Borentain, Stefanie Breitenstein, Martina Brueckmann, Nilo Cater, Andreas Clemens, Dobromir Dobrev, Sergio Dubner, Nils G. Edvardsson, Leif Friberg, Andreas Goette, Michele Gulizia, Robert Hatala, Jenny Horwood, Lukas Szumowski, Lukas Kappenberger, Josef Kautzner, Angelika Leute, Trudie Lobban, Ralf Meyer, Jay Millerhagen, John Morgan, Felix Muenzel, Michael Nabauer, Christoph Baertels, Michael Oeff, Dieter Paar, Juergen Polifka, Ursula Ravens, Ludger Rosin, Wim Stegink, Gerhard Steinbeck, Panos Vardas, Alphons Vincent, Maureen Walter, Guenter Breithardt, A. John Camm

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

147 Citations (Web of Science)

Abstract

While management of atrial fibrillation (AF) patients is improved by guideline-conform application of anticoagulant therapy, rate control, rhythm control, and therapy of accompanying heart disease, the morbidity and mortality associated with AF remain unacceptably high. This paper describes the proceedings of the 3rd Atrial Fibrillation NETwork (AFNET)/European Heart Rhythm Association (EHRA) consensus conference that convened over 60 scientists and representatives from industry to jointly discuss emerging therapeutic and diagnostic improvements to achieve better management of AF patients. The paper covers four chapters: (i) risk factors and risk markers for AF; (ii) pathophysiological classification of AF; (iii) relevance of monitored AF duration for AF-related outcomes; and (iv) perspectives and needs for implementing better antithrombotic therapy. Relevant published literature for each section is covered, and suggestions for the improvement of management in each area are put forward. Combined, the propositions formulate a perspective to implement comprehensive management in AF.

Original language	English
Pages (from-to)	8-27
Journal	EP Europace
Volume	14
Issue number	1
DOIs	https://doi.org/10.1093/europace/eur241
Publication status	Published - Jan 2012

Keywords

atrial fibrillation
management
outcomes
antithrombotic therapy
rate control
rhythm control
risk factors
early therapy

Access to Document

10.1093/europace/eur241

Cite this

Kirchhof, P., Lip, G. Y. H., Van Gelder, I. C., Bax, J., Hylek, E., Kaab, S., Schotten, U., Wegscheider, K., Boriani, G., Brandes, A., Ezekowitz, M. D., Diener, H-C., Haegeli, L., Heidbuchel, H., Lane, D. A., Mont, L., Willems, S., Dorian, P., Aunes-Jansson, M., ... Camm, A. J. (2012). Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options-a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference. EP Europace, 14(1), 8-27. https://doi.org/10.1093/europace/eur241

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title = "Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options-a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference",

abstract = "While management of atrial fibrillation (AF) patients is improved by guideline-conform application of anticoagulant therapy, rate control, rhythm control, and therapy of accompanying heart disease, the morbidity and mortality associated with AF remain unacceptably high. This paper describes the proceedings of the 3rd Atrial Fibrillation NETwork (AFNET)/European Heart Rhythm Association (EHRA) consensus conference that convened over 60 scientists and representatives from industry to jointly discuss emerging therapeutic and diagnostic improvements to achieve better management of AF patients. The paper covers four chapters: (i) risk factors and risk markers for AF; (ii) pathophysiological classification of AF; (iii) relevance of monitored AF duration for AF-related outcomes; and (iv) perspectives and needs for implementing better antithrombotic therapy. Relevant published literature for each section is covered, and suggestions for the improvement of management in each area are put forward. Combined, the propositions formulate a perspective to implement comprehensive management in AF.",

keywords = "atrial fibrillation, management, outcomes, antithrombotic therapy, rate control, rhythm control, risk factors, early therapy",

author = "Paulus Kirchhof and Lip, {Gregory Y. H.} and {Van Gelder}, {Isabelle C.} and Jeroen Bax and Elaine Hylek and Stefan Kaab and Ulrich Schotten and Karl Wegscheider and Giuseppe Boriani and Axel Brandes and Ezekowitz, {Michael D.} and Hans-Christoph Diener and Laurent Haegeli and Hein Heidbuchel and Lane, {Deirdre A.} and Luis Mont and Stephan Willems and Paul Dorian and Maria Aunes-Jansson and Carina Blomstrom-Lundqvist and Maria Borentain and Stefanie Breitenstein and Martina Brueckmann and Nilo Cater and Andreas Clemens and Dobromir Dobrev and Sergio Dubner and Edvardsson, {Nils G.} and Leif Friberg and Andreas Goette and Michele Gulizia and Robert Hatala and Jenny Horwood and Lukas Szumowski and Lukas Kappenberger and Josef Kautzner and Angelika Leute and Trudie Lobban and Ralf Meyer and Jay Millerhagen and John Morgan and Felix Muenzel and Michael Nabauer and Christoph Baertels and Michael Oeff and Dieter Paar and Juergen Polifka and Ursula Ravens and Ludger Rosin and Wim Stegink and Gerhard Steinbeck and Panos Vardas and Alphons Vincent and Maureen Walter and Guenter Breithardt and Camm, {A. John}",

year = "2012",

month = jan,

doi = "10.1093/europace/eur241",

language = "English",

volume = "14",

pages = "8--27",

journal = "EP Europace",

issn = "1099-5129",

publisher = "Oxford University Press",

number = "1",

}

Kirchhof, P, Lip, GYH, Van Gelder, IC, Bax, J, Hylek, E, Kaab, S, Schotten, U, Wegscheider, K, Boriani, G, Brandes, A, Ezekowitz, MD, Diener, H-C, Haegeli, L, Heidbuchel, H, Lane, DA, Mont, L, Willems, S, Dorian, P, Aunes-Jansson, M, Blomstrom-Lundqvist, C, Borentain, M, Breitenstein, S, Brueckmann, M, Cater, N, Clemens, A, Dobrev, D, Dubner, S, Edvardsson, NG, Friberg, L, Goette, A, Gulizia, M, Hatala, R, Horwood, J, Szumowski, L, Kappenberger, L, Kautzner, J, Leute, A, Lobban, T, Meyer, R, Millerhagen, J, Morgan, J, Muenzel, F, Nabauer, M, Baertels, C, Oeff, M, Paar, D, Polifka, J, Ravens, U, Rosin, L, Stegink, W, Steinbeck, G, Vardas, P, Vincent, A, Walter, M, Breithardt, G & Camm, AJ 2012, 'Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options-a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference', EP Europace, vol. 14, no. 1, pp. 8-27. https://doi.org/10.1093/europace/eur241

Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options-a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference. / Kirchhof, Paulus; Lip, Gregory Y. H.; Van Gelder, Isabelle C. et al.

In: EP Europace, Vol. 14, No. 1, 01.2012, p. 8-27.

Research output: Contribution to journal › Article › Academic › peer-review

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T1 - Comprehensive risk reduction in patients with atrial fibrillation: emerging diagnostic and therapeutic options-a report from the 3rd Atrial Fibrillation Competence NETwork/European Heart Rhythm Association consensus conference

AU - Kirchhof, Paulus

AU - Lip, Gregory Y. H.

AU - Van Gelder, Isabelle C.

AU - Bax, Jeroen

AU - Hylek, Elaine

AU - Kaab, Stefan

AU - Schotten, Ulrich

AU - Wegscheider, Karl

AU - Boriani, Giuseppe

AU - Brandes, Axel

AU - Ezekowitz, Michael D.

AU - Diener, Hans-Christoph

AU - Haegeli, Laurent

AU - Heidbuchel, Hein

AU - Lane, Deirdre A.

AU - Mont, Luis

AU - Willems, Stephan

AU - Dorian, Paul

AU - Aunes-Jansson, Maria

AU - Blomstrom-Lundqvist, Carina

AU - Borentain, Maria

AU - Breitenstein, Stefanie

AU - Brueckmann, Martina

AU - Cater, Nilo

AU - Clemens, Andreas

AU - Dobrev, Dobromir

AU - Dubner, Sergio

AU - Edvardsson, Nils G.

AU - Friberg, Leif

AU - Goette, Andreas

AU - Gulizia, Michele

AU - Hatala, Robert

AU - Horwood, Jenny

AU - Szumowski, Lukas

AU - Kappenberger, Lukas

AU - Kautzner, Josef

AU - Leute, Angelika

AU - Lobban, Trudie

AU - Meyer, Ralf

AU - Millerhagen, Jay

AU - Morgan, John

AU - Muenzel, Felix

AU - Nabauer, Michael

AU - Baertels, Christoph

AU - Oeff, Michael

AU - Paar, Dieter

AU - Polifka, Juergen

AU - Ravens, Ursula

AU - Rosin, Ludger

AU - Stegink, Wim

AU - Steinbeck, Gerhard

AU - Vardas, Panos

AU - Vincent, Alphons

AU - Walter, Maureen

AU - Breithardt, Guenter

AU - Camm, A. John

PY - 2012/1

Y1 - 2012/1

N2 - While management of atrial fibrillation (AF) patients is improved by guideline-conform application of anticoagulant therapy, rate control, rhythm control, and therapy of accompanying heart disease, the morbidity and mortality associated with AF remain unacceptably high. This paper describes the proceedings of the 3rd Atrial Fibrillation NETwork (AFNET)/European Heart Rhythm Association (EHRA) consensus conference that convened over 60 scientists and representatives from industry to jointly discuss emerging therapeutic and diagnostic improvements to achieve better management of AF patients. The paper covers four chapters: (i) risk factors and risk markers for AF; (ii) pathophysiological classification of AF; (iii) relevance of monitored AF duration for AF-related outcomes; and (iv) perspectives and needs for implementing better antithrombotic therapy. Relevant published literature for each section is covered, and suggestions for the improvement of management in each area are put forward. Combined, the propositions formulate a perspective to implement comprehensive management in AF.

AB - While management of atrial fibrillation (AF) patients is improved by guideline-conform application of anticoagulant therapy, rate control, rhythm control, and therapy of accompanying heart disease, the morbidity and mortality associated with AF remain unacceptably high. This paper describes the proceedings of the 3rd Atrial Fibrillation NETwork (AFNET)/European Heart Rhythm Association (EHRA) consensus conference that convened over 60 scientists and representatives from industry to jointly discuss emerging therapeutic and diagnostic improvements to achieve better management of AF patients. The paper covers four chapters: (i) risk factors and risk markers for AF; (ii) pathophysiological classification of AF; (iii) relevance of monitored AF duration for AF-related outcomes; and (iv) perspectives and needs for implementing better antithrombotic therapy. Relevant published literature for each section is covered, and suggestions for the improvement of management in each area are put forward. Combined, the propositions formulate a perspective to implement comprehensive management in AF.

KW - atrial fibrillation

KW - management

KW - outcomes

KW - antithrombotic therapy

KW - rate control

KW - rhythm control

KW - risk factors

KW - early therapy

U2 - 10.1093/europace/eur241

DO - 10.1093/europace/eur241

M3 - Article

VL - 14

SP - 8

EP - 27

JO - EP Europace

JF - EP Europace

SN - 1099-5129

IS - 1

ER -