Comprehensive biomarker analyses identifies HER2, EGFR, MET RNA expression and thymidylate synthase 5 ' UTR SNP as predictors of benefit from S-1 adjuvant chemotherapy in Japanese patients with stage II/III gastric cancer

Takaki Yoshikawa, Toru Aoyama, Kentaro Sakamaki, Takasi Oshima, Joyce Lin, Shenli Zhang, Nur Sabrina Sapari, Richie Soong, Iain Tan, Xiu Bin Chan, Dan Bottomley, Lindsay C. Hewitt, Tomio Arai, Bin Tean Teh, David Epstein, Takashi Ogata, Yoichi Kameda, Yohei Miyagi, Akira Tsuburaya, Satoshi MoritaHeike Grabsch, Patrick Tan

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)5130-5138
Number of pages9
JournalJournal of Cancer
Volume10
Issue number21
DOIs
Publication statusPublished - 2019

Keywords

  • COMPLEMENTING GENE-1 ERCC1
  • DIHYDROPYRIMIDINE DEHYDROGENASE
  • COLORECTAL-CANCER
  • PLUS CISPLATIN
  • GROWTH-FACTOR
  • REPEAT SEQUENCE
  • PATHWAY GENES
  • OUTCOMES
  • 5-FLUOROURACIL
  • POLYMORPHISMS

Cite this

Yoshikawa, T., Aoyama, T., Sakamaki, K., Oshima, T., Lin, J., Zhang, S., Sapari, N. S., Soong, R., Tan, I., Chan, X. B., Bottomley, D., Hewitt, L. C., Arai, T., Teh, B. T., Epstein, D., Ogata, T., Kameda, Y., Miyagi, Y., Tsuburaya, A., ... Tan, P. (2019). Comprehensive biomarker analyses identifies HER2, EGFR, MET RNA expression and thymidylate synthase 5 ' UTR SNP as predictors of benefit from S-1 adjuvant chemotherapy in Japanese patients with stage II/III gastric cancer. Journal of Cancer, 10(21), 5130-5138. https://doi.org/10.7150/jca.34741