Comprehensive analyses of RNA-seq and genome-wide data point to enrichment of neuronal cell type subsets in neuropsychiatric disorders

Keyphrases

• Neuropsychiatric Disorders 100%
• Neuropsychiatric 100%
• Neuronal Cells 100%
• Genome-wide Data 100%
• RNA Sequencing (RNA-seq) 100%
• RNA Genome 100%
• Genome-wide Association Study 66%
• Single-cell Transcriptomics 66%
• Psychiatric Disorders 66%
• Pyramidal Cells 66%
• Cell Enrichment 66%
• Genetic Loci 33%
• Cognitive Performance 33%
• Conclusive Evidence 33%
• Genetic Background 33%
• Human Genome 33%
• Bipolar Disorder 33%
• Schizophrenia 33%
• Autism Spectrum Disorder 33%
• Substance Use 33%
• Substance Use Disorder 33%
• Neurological Disorders 33%
• Genomic Data 33%
• Anorexia Nervosa 33%
• Related Traits 33%
• Astrocytes 33%
• Linkage Disequilibrium Score Regression 33%
• Shared Genetics 33%
• Neuron Cells 33%
• Genome Annotation 33%
• Complex Traits 33%
• Single Marker Analysis 33%
• Brain Cells 33%
• Enrichment Method 33%
• Consistency Degree 33%
• Medium Spiny Neurons 33%
• Mouse Brain Regions 33%
• 10X Genomics 33%
• Non-neuronal Cells 33%
• Transcriptomic Data 33%
• Large Degree 33%
• Karolinska Institutet 33%

Neuroscience

• Substance Abuse 100%
• Transcriptomics 100%
• Mental Disorder 100%
• Genome-Wide Association Study 100%
• Pyramidal Cell 100%
• RNA-Seq 100%
• Linkage Disequilibrium 50%
• Bipolar Disorder 50%
• Astrocyte 50%
• Anorexia Nervosa 50%
• Nervous System Disorder 50%
• Gene Locus 50%
• Autism Spectrum Disorder 50%
• Medium Spiny Neuron 50%
• Mouse Brain 50%

INIS

• data 100%
• brain 100%
• rna 100%
• datasets 100%
• enrichment 100%
• genetics 66%
• humans 33%
• symptoms 33%
• spectra 33%
• phenotype 33%
• mice 33%
• range 33%
• performance 33%
• psychological behavior 33%
• neurons 33%
• anorexia 33%