Comparison of postprandial oleic acid, 9c,11t CLA and 10t,12c CLA oxidation in healthy moderately overweight subjects

C. Malpuech Brugere, R.P. Mensink, O. Loreau, A. Maret, C.E. Fernie, T.S. Lassel, J.M. Chardigny*, C.M. Scrimgeour, J.L. Sebedio, B. Beaufrere

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Abstract

Few studies report the individual effect of 9c,11t- and 10t,12c-CLA on human energy metabolism. We compared the postprandial oxidative metabolism of 9c,11t- and 10t,12c-CLA and oleic acid (9c-18:1) in 22 healthy moderately overweight volunteers. After 24 weeks supplementation with 9c,11t-, 10t,12c-CLA or 9c-18:1 (3 g/day), subjects consumed a single oral bolus of the appropriate [1-(13)C]-labeled fatty acid. 8 h post-dose, cumulative oxidation was similar for 9c-18:1 and 10t,12c (P = 0.66), but significantly higher for 9c,11t (P < 0.01).
Original languageEnglish
Pages (from-to)1047-1051
Number of pages5
JournalLipids
Volume45
Issue number11
DOIs
Publication statusPublished - Nov 2010

Keywords

  • Human
  • (CO2)-C-13
  • Oxidation
  • Conjugated linoleic acid
  • CONJUGATED LINOLEIC-ACID
  • BODY-FAT ACCUMULATION
  • ENERGY-METABOLISM
  • SUPPLEMENTATION
  • ISOMERS

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