Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data

Tatyana Y. Doktorova; Heidrun Ellinger-Ziegelbauer; Mathieu Vinken; Tamara Vanhaecke; Joost van Delft; Jos Kleinjans; Hans-Juergen Ahr; Vera Rogiers

doi:10.1007/s00204-012-0946-8

Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data

Tatyana Y. Doktorova^*, Heidrun Ellinger-Ziegelbauer, Mathieu Vinken, Tamara Vanhaecke, Joost van Delft, Jos Kleinjans, Hans-Juergen Ahr, Vera Rogiers

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	1703-1715
Journal	Archives of Toxicology
Volume	86
Issue number	11
DOIs	https://doi.org/10.1007/s00204-012-0946-8
Publication status	Published - Nov 2012

Keywords

Genotoxic carcinogens
Global gene expression profiling
In vitro/in vivo relevance

Access to Document

10.1007/s00204-012-0946-8

Cite this

Doktorova, T. Y., Ellinger-Ziegelbauer, H., Vinken, M., Vanhaecke, T., van Delft, J., Kleinjans, J., Ahr, H-J., & Rogiers, V. (2012). Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data. Archives of Toxicology, 86(11), 1703-1715. https://doi.org/10.1007/s00204-012-0946-8

Doktorova, Tatyana Y. ; Ellinger-Ziegelbauer, Heidrun ; Vinken, Mathieu ; Vanhaecke, Tamara ; van Delft, Joost ; Kleinjans, Jos ; Ahr, Hans-Juergen ; Rogiers, Vera. / Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data. In: Archives of Toxicology. 2012 ; Vol. 86, No. 11. pp. 1703-1715.

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title = "Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data",

keywords = "Genotoxic carcinogens, Global gene expression profiling, In vitro/in vivo relevance",

author = "Doktorova, {Tatyana Y.} and Heidrun Ellinger-Ziegelbauer and Mathieu Vinken and Tamara Vanhaecke and {van Delft}, Joost and Jos Kleinjans and Hans-Juergen Ahr and Vera Rogiers",

year = "2012",

month = nov,

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language = "English",

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Doktorova, TY, Ellinger-Ziegelbauer, H, Vinken, M, Vanhaecke, T, van Delft, J, Kleinjans, J, Ahr, H-J & Rogiers, V 2012, 'Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data', Archives of Toxicology, vol. 86, no. 11, pp. 1703-1715. https://doi.org/10.1007/s00204-012-0946-8

Comparison of genotoxicant-modified transcriptomic responses in conventional and epigenetically stabilized primary rat hepatocytes with in vivo rat liver data. / Doktorova, Tatyana Y.; Ellinger-Ziegelbauer, Heidrun; Vinken, Mathieu; Vanhaecke, Tamara; van Delft, Joost; Kleinjans, Jos; Ahr, Hans-Juergen; Rogiers, Vera.

In: Archives of Toxicology, Vol. 86, No. 11, 11.2012, p. 1703-1715.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Doktorova, Tatyana Y.

AU - Ellinger-Ziegelbauer, Heidrun

AU - Vinken, Mathieu

AU - Vanhaecke, Tamara

AU - van Delft, Joost

AU - Kleinjans, Jos

AU - Ahr, Hans-Juergen

AU - Rogiers, Vera

PY - 2012/11

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KW - Genotoxic carcinogens

KW - Global gene expression profiling

KW - In vitro/in vivo relevance

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DO - 10.1007/s00204-012-0946-8

M3 - Article

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VL - 86

SP - 1703

EP - 1715

JO - Archives of Toxicology

JF - Archives of Toxicology

SN - 0340-5761

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