Comparing in vitro human liver models to in vivo human liver using RNA-Seq

Rajinder Gupta, Yannick Schrooders, Duncan Hauser, Marcel van Herwijnen, Wiebke Albrecht, Bas ter Braak, Tim Brecklinghaus, Jose V. Castell, Leroy Elenschneider, Sylvia Escher, Patrick Guye, Jan G. Hengstler, Ahmed Ghallab, Tanja Hansen, Marcel Leist, Richard Maclennan, Wolfgang Moritz, Laia Tolosa, Tine Tricot, Catherine VerfailliePaul Walker, Bob van de Water, Jos Kleinjans, Florian Caiment*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

6 Citations (Web of Science)
Original languageEnglish
Pages (from-to)573-589
Number of pages17
JournalArchives of Toxicology
Volume95
Issue number2
Early online date27 Oct 2020
DOIs
Publication statusPublished - Feb 2021

Keywords

  • In vivo liver
  • In vitro liver
  • RNA-seq
  • CellNet
  • Non-DEGs
  • Non-DEGs(DTU)
  • Pathway coverage
  • HEPARG CELLS
  • PRIMARY HEPATOCYTES
  • TOXICITY
  • DIFFERENTIATION
  • HEPATOTOXICITY
  • METABOLISM
  • INDUCTION
  • EVOLUTION
  • PLATFORM
  • SYSTEMS

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