Abstract
For the treatment and prevention of ocular diseases, eye drops or ointments are generally prescribed to patients. However, these conventional drug formulations suffer from low patient compliance and deliver a suboptimal low drug concentration at the target site. Therefore, new drug–device combinations are being explored to improve drug delivery to the eye.
Various drug–device combinations have been developed in the last few decades, while only a few have made it to the market. In this chapter, we provide a comprehensive overview of drug–device combinations that have reached the final preclinical and clinical stages. We focus on devices that are marketed for ocular diseases such as glaucoma, dry eye disease, infections, and inflammations. Furthermore, drug delivery devices for ocular surgeries are discussed.
Various drug–device combinations have been developed in the last few decades, while only a few have made it to the market. In this chapter, we provide a comprehensive overview of drug–device combinations that have reached the final preclinical and clinical stages. We focus on devices that are marketed for ocular diseases such as glaucoma, dry eye disease, infections, and inflammations. Furthermore, drug delivery devices for ocular surgeries are discussed.
| Original language | English |
|---|---|
| Title of host publication | Combination Drug Delivery Approach as an Effective Therapy for Various Diseases |
| Editors | Prashant Kesharwani |
| Publisher | Elsevier |
| Pages | 47-63 |
| Number of pages | 17 |
| Edition | 1 |
| ISBN (Print) | 9780323858731 |
| DOIs | |
| Publication status | Published - 2022 |