Colonization with Pseudomonas aeruginosa in patients developing ventilator-associated pneumonia.

D.C.J.J. Bergmans, M.J. Bonten, E.E. Stobberingh, F.H. van Tiel, S. van der Geest, P.W. de Leeuw, C.E. Gaillard

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Abstract

Department of Internal Medicine, University Hospital Maastricht, The Netherlands.

To determine routes of colonization and genotypic variation of Pseudomonas aeruginosa leading to ventilator-associated pneumonia, colonization of the rectum, stomach, oropharynx, and trachea was studied chronologically in 10 patients. Ninety-one isolates of P aeruginosa were genotyped; seven different genotypes were identified. Patients developing ventilator-associated pneumonia caused by P aeruginosa were colonized at multiple body sites and may be colonized with multiple genotypes. The upper respiratory tract is the predominant initial site of colonization with P aeruginosa.
Original languageEnglish
Pages (from-to)853-855
Number of pages3
JournalInfection Control and Hospital Epidemiology
Volume19
Issue number11
DOIs
Publication statusPublished - 1 Jan 1998

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