Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe

S.E. Gerritsen; A. Maras; L.S. van Bodegom; M.M. Overbeek; F.C. Verhulst; D. Wolke; R. Appleton; A. Bertani; M.G. Cataldo; P. Conti; D. Da Fonseca; N. Davidovic; K. Dodig-Curkovic; C. Ferrari; F. Fiori; T. Franic; C. Gatherer; G. De Girolamo; N. Heaney; G. Hendrickx; A. Kolozsvari; F.M. Levi; K. Lievesley; J. Madan; O. Martinelli; M. Mastroianni; V. Maurice; F. McNicholas; L. O'Hara; M. Paul; D. Purper-Ouakil; V. de Roeck; F. Russet; M.C. Saam; I. Sagar-Ouriaghli; P.J. Santosh; A. Sartor; A. Schandrin; U.M.E. Schulze; G. Signorini; S.P. Singh; J. Singh; C. Street; P. Tah; E. Tanase; S. Tremmery; A. Tuffrey; H. Tuomainen; T.A.M.J. van Amelsvoort; A. Wilson; Milestone Consortium; Gwen C. Dieleman

doi:10.1136/bmjopen-2021-053373

Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe

S.E. Gerritsen, A. Maras, L.S. van Bodegom, M.M. Overbeek, F.C. Verhulst, D. Wolke, R. Appleton, A. Bertani, M.G. Cataldo, P. Conti, D. Da Fonseca, N. Davidovic, K. Dodig-Curkovic, C. Ferrari, F. Fiori, T. Franic, C. Gatherer, G. De Girolamo, N. Heaney, G. HendrickxA. Kolozsvari, F.M. Levi, K. Lievesley, J. Madan, O. Martinelli, M. Mastroianni, V. Maurice, F. McNicholas, L. O'Hara, M. Paul, D. Purper-Ouakil, V. de Roeck, F. Russet, M.C. Saam, I. Sagar-Ouriaghli, P.J. Santosh, A. Sartor, A. Schandrin, U.M.E. Schulze, G. Signorini, S.P. Singh, J. Singh, C. Street, P. Tah, E. Tanase, S. Tremmery, A. Tuffrey, H. Tuomainen, T.A.M.J. van Amelsvoort, A. Wilson, Milestone Consortium, Gwen C. Dieleman^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

6 Citations (Web of Science)

Abstract

Purpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports.Participants Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at.Findings to date This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be 'markedly ill', 'severely ill' or 'among the most extremely ill' by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year.Future plans Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared.

Original language	English
Article number	e053373
Number of pages	15
Journal	BMJ Open
Volume	11
Issue number	12
DOIs	https://doi.org/10.1136/bmjopen-2021-053373
Publication status	Published - 1 Dec 2021

Keywords

child & adolescent psychiatry
adult psychiatry
international health services
QUALITY-OF-LIFE
WHOQOL-BREF
TRANSITION
ADOLESCENT
EXPERIENCE
OUTCOMES
SAMPLE
SCALE
CROSS

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Gerritsen, S. E., Maras, A., van Bodegom, L. S., Overbeek, M. M., Verhulst, F. C., Wolke, D., Appleton, R., Bertani, A., Cataldo, M. G., Conti, P., Da Fonseca, D., Davidovic, N., Dodig-Curkovic, K., Ferrari, C., Fiori, F., Franic, T., Gatherer, C., De Girolamo, G., Heaney, N., ... Dieleman, G. C. (2021). Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe. BMJ Open, 11(12), [e053373]. https://doi.org/10.1136/bmjopen-2021-053373

@article{565252df8eb44d8ea5c943dfa4f92630,

title = "Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe",

abstract = "Purpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports.Participants Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at.Findings to date This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be 'markedly ill', 'severely ill' or 'among the most extremely ill' by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year.Future plans Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared.",

keywords = "child & adolescent psychiatry, adult psychiatry, international health services, QUALITY-OF-LIFE, WHOQOL-BREF, TRANSITION, ADOLESCENT, EXPERIENCE, OUTCOMES, SAMPLE, SCALE, CROSS",

author = "S.E. Gerritsen and A. Maras and {van Bodegom}, L.S. and M.M. Overbeek and F.C. Verhulst and D. Wolke and R. Appleton and A. Bertani and M.G. Cataldo and P. Conti and {Da Fonseca}, D. and N. Davidovic and K. Dodig-Curkovic and C. Ferrari and F. Fiori and T. Franic and C. Gatherer and {De Girolamo}, G. and N. Heaney and G. Hendrickx and A. Kolozsvari and F.M. Levi and K. Lievesley and J. Madan and O. Martinelli and M. Mastroianni and V. Maurice and F. McNicholas and L. O'Hara and M. Paul and D. Purper-Ouakil and {de Roeck}, V. and F. Russet and M.C. Saam and I. Sagar-Ouriaghli and P.J. Santosh and A. Sartor and A. Schandrin and U.M.E. Schulze and G. Signorini and S.P. Singh and J. Singh and C. Street and P. Tah and E. Tanase and S. Tremmery and A. Tuffrey and H. Tuomainen and {van Amelsvoort}, T.A.M.J. and A. Wilson and {Milestone Consortium} and Dieleman, {Gwen C.}",

year = "2021",

month = dec,

day = "1",

doi = "10.1136/bmjopen-2021-053373",

language = "English",

volume = "11",

journal = "BMJ Open",

issn = "2044-6055",

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Gerritsen, SE, Maras, A, van Bodegom, LS, Overbeek, MM, Verhulst, FC, Wolke, D, Appleton, R, Bertani, A, Cataldo, MG, Conti, P, Da Fonseca, D, Davidovic, N, Dodig-Curkovic, K, Ferrari, C, Fiori, F, Franic, T, Gatherer, C, De Girolamo, G, Heaney, N, Hendrickx, G, Kolozsvari, A, Levi, FM, Lievesley, K, Madan, J, Martinelli, O, Mastroianni, M, Maurice, V, McNicholas, F, O'Hara, L, Paul, M, Purper-Ouakil, D, de Roeck, V, Russet, F, Saam, MC, Sagar-Ouriaghli, I, Santosh, PJ, Sartor, A, Schandrin, A, Schulze, UME, Signorini, G, Singh, SP, Singh, J, Street, C, Tah, P, Tanase, E, Tremmery, S, Tuffrey, A, Tuomainen, H, van Amelsvoort, TAMJ, Wilson, A, Milestone Consortium & Dieleman, GC 2021, 'Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe', BMJ Open, vol. 11, no. 12, e053373. https://doi.org/10.1136/bmjopen-2021-053373

Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe. / Gerritsen, S.E.; Maras, A.; van Bodegom, L.S. et al.
In: BMJ Open, Vol. 11, No. 12, e053373, 01.12.2021.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Cohort profile: demographic and clinical characteristics of the MILESTONE longitudinal cohort of young people approaching the upper age limit of their child mental health care service in Europe

AU - Gerritsen, S.E.

AU - Maras, A.

AU - van Bodegom, L.S.

AU - Overbeek, M.M.

AU - Verhulst, F.C.

AU - Wolke, D.

AU - Appleton, R.

AU - Bertani, A.

AU - Cataldo, M.G.

AU - Conti, P.

AU - Da Fonseca, D.

AU - Davidovic, N.

AU - Dodig-Curkovic, K.

AU - Ferrari, C.

AU - Fiori, F.

AU - Franic, T.

AU - Gatherer, C.

AU - De Girolamo, G.

AU - Heaney, N.

AU - Hendrickx, G.

AU - Kolozsvari, A.

AU - Levi, F.M.

AU - Lievesley, K.

AU - Madan, J.

AU - Martinelli, O.

AU - Mastroianni, M.

AU - Maurice, V.

AU - McNicholas, F.

AU - O'Hara, L.

AU - Paul, M.

AU - Purper-Ouakil, D.

AU - de Roeck, V.

AU - Russet, F.

AU - Saam, M.C.

AU - Sagar-Ouriaghli, I.

AU - Santosh, P.J.

AU - Sartor, A.

AU - Schandrin, A.

AU - Schulze, U.M.E.

AU - Signorini, G.

AU - Singh, S.P.

AU - Singh, J.

AU - Street, C.

AU - Tah, P.

AU - Tanase, E.

AU - Tremmery, S.

AU - Tuffrey, A.

AU - Tuomainen, H.

AU - van Amelsvoort, T.A.M.J.

AU - Wilson, A.

AU - Milestone Consortium

AU - Dieleman, Gwen C.

PY - 2021/12/1

Y1 - 2021/12/1

N2 - Purpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports.Participants Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at.Findings to date This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be 'markedly ill', 'severely ill' or 'among the most extremely ill' by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year.Future plans Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared.

AB - Purpose The presence of distinct child and adolescent mental health services (CAMHS) and adult mental health services (AMHS) impacts continuity of mental health treatment for young people. However, we do not know the extent of discontinuity of care in Europe nor the effects of discontinuity on the mental health of young people. Current research is limited, as the majority of existing studies are retrospective, based on small samples or used non-standardised information from medical records. The MILESTONE prospective cohort study aims to examine associations between service use, mental health and other outcomes over 24 months, using information from self, parent and clinician reports.Participants Seven hundred sixty-three young people from 39 CAMHS in 8 European countries, their parents and CAMHS clinicians who completed interviews and online questionnaires and were followed up for 2 years after reaching the upper age limit of the CAMHS they receive treatment at.Findings to date This cohort profile describes the baseline characteristics of the MILESTONE cohort. The mental health of young people reaching the upper age limit of their CAMHS varied greatly in type and severity: 32.8% of young people reported clinical levels of self-reported problems and 18.6% were rated to be 'markedly ill', 'severely ill' or 'among the most extremely ill' by their clinician. Fifty-seven per cent of young people reported psychotropic medication use in the previous half year.Future plans Analysis of longitudinal data from the MILESTONE cohort will be used to assess relationships between the demographic and clinical characteristics of young people reaching the upper age limit of their CAMHS and the type of care the young person uses over the next 2 years, such as whether the young person transitions to AMHS. At 2 years follow-up, the mental health outcomes of young people following different care pathways will be compared.

KW - child & adolescent psychiatry

KW - adult psychiatry

KW - international health services

KW - QUALITY-OF-LIFE

KW - WHOQOL-BREF

KW - TRANSITION

KW - ADOLESCENT

KW - EXPERIENCE

KW - OUTCOMES

KW - SAMPLE

KW - SCALE

KW - CROSS

U2 - 10.1136/bmjopen-2021-053373

DO - 10.1136/bmjopen-2021-053373

M3 - Article

C2 - 34916319

SN - 2044-6055

VL - 11

JO - BMJ Open

JF - BMJ Open

IS - 12

M1 - e053373

ER -