Cognitive performance in relation to MRI temporal lobe volume in schizophrenic patients and healthy control subjects.

A.C. Krabbendam; M M A. Derix; A. Honig; E.F.P.M. Vuurman; R.C. Havermans; J.T. Wilmink; J. Jolles

doi:10.1176/appi.neuropsych.12.2.251

Cognitive performance in relation to MRI temporal lobe volume in schizophrenic patients and healthy control subjects.

A.C. Krabbendam^*, M M A. Derix, A. Honig, E.F.P.M. Vuurman, R.C. Havermans, J.T. Wilmink, J. Jolles

^*Corresponding author for this work

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Abstract

The aim of this study was to identify whether specific deficits in cognitive processing are present in schizophrenia and whether these ave related to the volume of temporal and limbic structures. Twenty-seven schizophrenic outpatients were compared with 19 matched control subjects. Compared with control subjects, patients performed complex tasks disproportionately worse than they performed simple tasks, No group differences were found with regard to temporal and limbic volume. Volume of the parahippocampal gyrus was correlate with cognitive performance. The findings are interpreted as evidence for a dysfunction in the maintenance of task-relevant information and the inhibition of irrelevant information.

Original language	English
Pages (from-to)	251-256
Journal	Journal of Neuropsychiatry and Clinical Neurosciences
Volume	12
DOIs	https://doi.org/10.1176/appi.neuropsych.12.2.251
Publication status	Published - 1 Jan 2000

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title = "Cognitive performance in relation to MRI temporal lobe volume in schizophrenic patients and healthy control subjects.",

abstract = "The aim of this study was to identify whether specific deficits in cognitive processing are present in schizophrenia and whether these ave related to the volume of temporal and limbic structures. Twenty-seven schizophrenic outpatients were compared with 19 matched control subjects. Compared with control subjects, patients performed complex tasks disproportionately worse than they performed simple tasks, No group differences were found with regard to temporal and limbic volume. Volume of the parahippocampal gyrus was correlate with cognitive performance. The findings are interpreted as evidence for a dysfunction in the maintenance of task-relevant information and the inhibition of irrelevant information.",

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AU - Krabbendam, A.C.

AU - Derix, M M A.

AU - Honig, A.

AU - Vuurman, E.F.P.M.

AU - Havermans, R.C.

AU - Wilmink, J.T.

AU - Jolles, J.

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AB - The aim of this study was to identify whether specific deficits in cognitive processing are present in schizophrenia and whether these ave related to the volume of temporal and limbic structures. Twenty-seven schizophrenic outpatients were compared with 19 matched control subjects. Compared with control subjects, patients performed complex tasks disproportionately worse than they performed simple tasks, No group differences were found with regard to temporal and limbic volume. Volume of the parahippocampal gyrus was correlate with cognitive performance. The findings are interpreted as evidence for a dysfunction in the maintenance of task-relevant information and the inhibition of irrelevant information.

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DO - 10.1176/appi.neuropsych.12.2.251

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JO - Journal of Neuropsychiatry and Clinical Neurosciences

JF - Journal of Neuropsychiatry and Clinical Neurosciences

ER -

Cognitive performance in relation to MRI temporal lobe volume in schizophrenic patients and healthy control subjects.

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