Coffee and tea consumption in relation to prostate cancer prognosis

Milan S. Geybels, Marian L. Neuhouser, Jonathan L. Wright, Marni Stott-Miller, Janet L. Stanford*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

15 Citations (Web of Science)

Abstract

Bioactive compounds found in coffee and tea may delay the progression of prostate cancer. We investigated associations of pre-diagnostic coffee and tea consumption with risk of prostate cancer recurrence/progression. Study participants were men diagnosed with prostate cancer in 2002-2005 in King County, Washington, USA. We assessed the usual pattern of coffee and tea consumption two years before diagnosis date. Prostate cancer-specific outcome events were identified using a detailed follow-up survey. Multivariable Cox proportional hazards regression models were used to estimate hazard ratios (HRs) and 95 % confidence intervals (CIs). The analysis of coffee intake in relation to prostate cancer recurrence/progression included 630 patients with a median follow-up of 6.4 years, during which 140 prostate cancer recurrence/progression events were recorded. Approximately 61 % of patients consumed at least one cup of coffee per day. Coffee consumption was associated with a reduced risk of prostate cancer recurrence/progression; the adjusted HR for a parts per thousand yen4 cups/day versus a parts per thousand currency sign1 cup/week was 0.41 (95 % CI: 0.20, 0.81; p for trend = 0.01). Approximately 14 % of patients consumed one or more cups of tea per day, and tea consumption was unrelated to prostate cancer recurrence/progression. Results indicate that higher pre-diagnostic coffee consumption is associated with a lower risk of prostate cancer recurrence/progression. This finding will require replication in larger studies.
Original languageEnglish
Pages (from-to)1947-1954
JournalCancer Causes & Control
Volume24
Issue number11
DOIs
Publication statusPublished - Nov 2013

Keywords

  • Prostate cancer
  • Progression
  • Biochemical recurrence
  • Mortality
  • Coffee
  • Tea

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