Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis

Marieke G. M. Braem; N. Charlotte Onland-Moret; Leo J. Schouten; Anne Tjonneland; Louise Hansen; Christina C. Dahm; Kim Overvad; Annekatrin Lukanova; Laure Dossus; Anna Floegel; Heiner Boeing; Francoise Clavel-Chapelon; Nathalie Chabbert-Buffet; Guy Fagherazzi; Antonia Trichopoulou; Vassiliki Benetou; Ioulia Goufa; Valeria Pala; Rocco Galasso; Amalia Mattiello; Carlotta Sacerdote; Domenico Palli; Rosario Tumino; Inger T. Gram; Eiliv Lund; Oxana Gavrilyuk; Maria-Jose Sanchez; Ramon Quiros; Carlos A. Gonzales; Miren Dorronsoro; Jose M. Huerta Castano; Aurelio Barricarte Gurrea; Annika Idahl; Nina Ohlson; Eva Lundin; Karin Jirstrom; Elisabet Witfalt; Naomi E. Allen; Konstantinos K. Tsilidis; Kay-Tee Kaw; H. Bas Bueno-de-Mesquita; Vincent K. Dik; Sabina Rinaldi; Veronika Fedirko; Teresa Norat; Elio Riboli; Rudolf Kaaks; Petra H. M. Peeters

doi:10.3945/ajcn.111.026393

Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis

Marieke G. M. Braem^*, N. Charlotte Onland-Moret, Leo J. Schouten, Anne Tjonneland, Louise Hansen, Christina C. Dahm, Kim Overvad, Annekatrin Lukanova, Laure Dossus, Anna Floegel, Heiner Boeing, Francoise Clavel-Chapelon, Nathalie Chabbert-Buffet, Guy Fagherazzi, Antonia Trichopoulou, Vassiliki Benetou, Ioulia Goufa, Valeria Pala, Rocco Galasso, Amalia MattielloCarlotta Sacerdote, Domenico Palli, Rosario Tumino, Inger T. Gram, Eiliv Lund, Oxana Gavrilyuk, Maria-Jose Sanchez, Ramon Quiros, Carlos A. Gonzales, Miren Dorronsoro, Jose M. Huerta Castano, Aurelio Barricarte Gurrea, Annika Idahl, Nina Ohlson, Eva Lundin, Karin Jirstrom, Elisabet Witfalt, Naomi E. Allen, Konstantinos K. Tsilidis, Kay-Tee Kaw, H. Bas Bueno-de-Mesquita, Vincent K. Dik, Sabina Rinaldi, Veronika Fedirko, Teresa Norat, Elio Riboli, Rudolf Kaaks, Petra H. M. Peeters

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

Abstract

Background: In 2007 the World Cancer Research Fund Report concluded that there was limited and inconsistent evidence for an effect of coffee and tea consumption on the risk of epithelial ovarian cancer (EOC). Objective: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we aimed to investigate whether coffee intakes, tea intakes, or both are associated with the risk of EOC. Design: All women participating in the EPIC (n = 330,849) were included in this study. Data on coffee and tea consumption were collected through validated food-frequency questionnaires at baseline. HRs and 95% CIs were estimated by using Cox proportional hazards models. Furthermore, we performed an updated meta-analysis of all previous prospective studies until April 2011 by comparing the highest and lowest coffee- and tea-consumption categories as well as by using dose-response random-effects meta-regression analyses. Results: During a median follow-up of 11.7 y, 1244 women developed EOC. No association was observed between the risk of EOC and coffee consumption [HR: 1.05 (95% CI: 0.75, 1.46) for the top quintile compared with no intake] or tea consumption [HR: 1.07 (95% Cl: 0.78, 1.45) for the top quintile compared with no intake]. This lack of association between coffee and tea intake and EOC risk was confirmed by the results of our meta-analysis. Conclusion: Epidemiologic studies do not provide sufficient evidence to support an association between coffee and tea consumption and risk of ovarian cancer. Am J Clin Nutr 2012;95:1172-81.

Original language	English
Pages (from-to)	1172-1181
Journal	American Journal of Clinical Nutrition
Volume	95
Issue number	5
DOIs	https://doi.org/10.3945/ajcn.111.026393
Publication status	Published - May 2012

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Braem, M. G. M., Onland-Moret, N. C., Schouten, L. J., Tjonneland, A., Hansen, L., Dahm, C. C., Overvad, K., Lukanova, A., Dossus, L., Floegel, A., Boeing, H., Clavel-Chapelon, F., Chabbert-Buffet, N., Fagherazzi, G., Trichopoulou, A., Benetou, V., Goufa, I., Pala, V., Galasso, R., ... Peeters, P. H. M. (2012). Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis. American Journal of Clinical Nutrition, 95(5), 1172-1181. https://doi.org/10.3945/ajcn.111.026393

@article{7131e28ffb484f8b86b79335ed830f0f,

title = "Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis",

abstract = "Background: In 2007 the World Cancer Research Fund Report concluded that there was limited and inconsistent evidence for an effect of coffee and tea consumption on the risk of epithelial ovarian cancer (EOC). Objective: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we aimed to investigate whether coffee intakes, tea intakes, or both are associated with the risk of EOC. Design: All women participating in the EPIC (n = 330,849) were included in this study. Data on coffee and tea consumption were collected through validated food-frequency questionnaires at baseline. HRs and 95% CIs were estimated by using Cox proportional hazards models. Furthermore, we performed an updated meta-analysis of all previous prospective studies until April 2011 by comparing the highest and lowest coffee- and tea-consumption categories as well as by using dose-response random-effects meta-regression analyses. Results: During a median follow-up of 11.7 y, 1244 women developed EOC. No association was observed between the risk of EOC and coffee consumption [HR: 1.05 (95% CI: 0.75, 1.46) for the top quintile compared with no intake] or tea consumption [HR: 1.07 (95% Cl: 0.78, 1.45) for the top quintile compared with no intake]. This lack of association between coffee and tea intake and EOC risk was confirmed by the results of our meta-analysis. Conclusion: Epidemiologic studies do not provide sufficient evidence to support an association between coffee and tea consumption and risk of ovarian cancer. Am J Clin Nutr 2012;95:1172-81.",

author = "Braem, {Marieke G. M.} and Onland-Moret, {N. Charlotte} and Schouten, {Leo J.} and Anne Tjonneland and Louise Hansen and Dahm, {Christina C.} and Kim Overvad and Annekatrin Lukanova and Laure Dossus and Anna Floegel and Heiner Boeing and Francoise Clavel-Chapelon and Nathalie Chabbert-Buffet and Guy Fagherazzi and Antonia Trichopoulou and Vassiliki Benetou and Ioulia Goufa and Valeria Pala and Rocco Galasso and Amalia Mattiello and Carlotta Sacerdote and Domenico Palli and Rosario Tumino and Gram, {Inger T.} and Eiliv Lund and Oxana Gavrilyuk and Maria-Jose Sanchez and Ramon Quiros and Gonzales, {Carlos A.} and Miren Dorronsoro and {Huerta Castano}, {Jose M.} and {Barricarte Gurrea}, Aurelio and Annika Idahl and Nina Ohlson and Eva Lundin and Karin Jirstrom and Elisabet Witfalt and Allen, {Naomi E.} and Tsilidis, {Konstantinos K.} and Kay-Tee Kaw and Bueno-de-Mesquita, {H. Bas} and Dik, {Vincent K.} and Sabina Rinaldi and Veronika Fedirko and Teresa Norat and Elio Riboli and Rudolf Kaaks and Peeters, {Petra H. M.}",

year = "2012",

month = may,

doi = "10.3945/ajcn.111.026393",

language = "English",

volume = "95",

pages = "1172--1181",

journal = "American Journal of Clinical Nutrition",

issn = "0002-9165",

publisher = "Elsevier Inc.",

number = "5",

}

Braem, MGM, Onland-Moret, NC, Schouten, LJ, Tjonneland, A, Hansen, L, Dahm, CC, Overvad, K, Lukanova, A, Dossus, L, Floegel, A, Boeing, H, Clavel-Chapelon, F, Chabbert-Buffet, N, Fagherazzi, G, Trichopoulou, A, Benetou, V, Goufa, I, Pala, V, Galasso, R, Mattiello, A, Sacerdote, C, Palli, D, Tumino, R, Gram, IT, Lund, E, Gavrilyuk, O, Sanchez, M-J, Quiros, R, Gonzales, CA, Dorronsoro, M, Huerta Castano, JM, Barricarte Gurrea, A, Idahl, A, Ohlson, N, Lundin, E, Jirstrom, K, Witfalt, E, Allen, NE, Tsilidis, KK, Kaw, K-T, Bueno-de-Mesquita, HB, Dik, VK, Rinaldi, S, Fedirko, V, Norat, T, Riboli, E, Kaaks, R & Peeters, PHM 2012, 'Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis', American Journal of Clinical Nutrition, vol. 95, no. 5, pp. 1172-1181. https://doi.org/10.3945/ajcn.111.026393

TY - JOUR

T1 - Coffee and tea consumption and the risk of ovarian cancer: a prospective cohort study and updated meta-analysis

AU - Braem, Marieke G. M.

AU - Onland-Moret, N. Charlotte

AU - Schouten, Leo J.

AU - Tjonneland, Anne

AU - Hansen, Louise

AU - Dahm, Christina C.

AU - Overvad, Kim

AU - Lukanova, Annekatrin

AU - Dossus, Laure

AU - Floegel, Anna

AU - Boeing, Heiner

AU - Clavel-Chapelon, Francoise

AU - Chabbert-Buffet, Nathalie

AU - Fagherazzi, Guy

AU - Trichopoulou, Antonia

AU - Benetou, Vassiliki

AU - Goufa, Ioulia

AU - Pala, Valeria

AU - Galasso, Rocco

AU - Mattiello, Amalia

AU - Sacerdote, Carlotta

AU - Palli, Domenico

AU - Tumino, Rosario

AU - Gram, Inger T.

AU - Lund, Eiliv

AU - Gavrilyuk, Oxana

AU - Sanchez, Maria-Jose

AU - Quiros, Ramon

AU - Gonzales, Carlos A.

AU - Dorronsoro, Miren

AU - Huerta Castano, Jose M.

AU - Barricarte Gurrea, Aurelio

AU - Idahl, Annika

AU - Ohlson, Nina

AU - Lundin, Eva

AU - Jirstrom, Karin

AU - Witfalt, Elisabet

AU - Allen, Naomi E.

AU - Tsilidis, Konstantinos K.

AU - Kaw, Kay-Tee

AU - Bueno-de-Mesquita, H. Bas

AU - Dik, Vincent K.

AU - Rinaldi, Sabina

AU - Fedirko, Veronika

AU - Norat, Teresa

AU - Riboli, Elio

AU - Kaaks, Rudolf

AU - Peeters, Petra H. M.

PY - 2012/5

Y1 - 2012/5

N2 - Background: In 2007 the World Cancer Research Fund Report concluded that there was limited and inconsistent evidence for an effect of coffee and tea consumption on the risk of epithelial ovarian cancer (EOC). Objective: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we aimed to investigate whether coffee intakes, tea intakes, or both are associated with the risk of EOC. Design: All women participating in the EPIC (n = 330,849) were included in this study. Data on coffee and tea consumption were collected through validated food-frequency questionnaires at baseline. HRs and 95% CIs were estimated by using Cox proportional hazards models. Furthermore, we performed an updated meta-analysis of all previous prospective studies until April 2011 by comparing the highest and lowest coffee- and tea-consumption categories as well as by using dose-response random-effects meta-regression analyses. Results: During a median follow-up of 11.7 y, 1244 women developed EOC. No association was observed between the risk of EOC and coffee consumption [HR: 1.05 (95% CI: 0.75, 1.46) for the top quintile compared with no intake] or tea consumption [HR: 1.07 (95% Cl: 0.78, 1.45) for the top quintile compared with no intake]. This lack of association between coffee and tea intake and EOC risk was confirmed by the results of our meta-analysis. Conclusion: Epidemiologic studies do not provide sufficient evidence to support an association between coffee and tea consumption and risk of ovarian cancer. Am J Clin Nutr 2012;95:1172-81.

AB - Background: In 2007 the World Cancer Research Fund Report concluded that there was limited and inconsistent evidence for an effect of coffee and tea consumption on the risk of epithelial ovarian cancer (EOC). Objective: In the European Prospective Investigation into Cancer and Nutrition (EPIC), we aimed to investigate whether coffee intakes, tea intakes, or both are associated with the risk of EOC. Design: All women participating in the EPIC (n = 330,849) were included in this study. Data on coffee and tea consumption were collected through validated food-frequency questionnaires at baseline. HRs and 95% CIs were estimated by using Cox proportional hazards models. Furthermore, we performed an updated meta-analysis of all previous prospective studies until April 2011 by comparing the highest and lowest coffee- and tea-consumption categories as well as by using dose-response random-effects meta-regression analyses. Results: During a median follow-up of 11.7 y, 1244 women developed EOC. No association was observed between the risk of EOC and coffee consumption [HR: 1.05 (95% CI: 0.75, 1.46) for the top quintile compared with no intake] or tea consumption [HR: 1.07 (95% Cl: 0.78, 1.45) for the top quintile compared with no intake]. This lack of association between coffee and tea intake and EOC risk was confirmed by the results of our meta-analysis. Conclusion: Epidemiologic studies do not provide sufficient evidence to support an association between coffee and tea consumption and risk of ovarian cancer. Am J Clin Nutr 2012;95:1172-81.

U2 - 10.3945/ajcn.111.026393

DO - 10.3945/ajcn.111.026393

M3 - Article

C2 - 22440851

SN - 0002-9165

VL - 95

SP - 1172

EP - 1181

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

IS - 5

ER -