Closed incisional negative pressure therapy may reduce surgical site infection rate following endophlebectomy with complementary polytetrafluoroethylene arteriovenous fistula of the common femoral vein

A. Gombert*, T.M.A.J. Van Vuuren, M.E. Barbati, I.M. Toonder, J.H.H. Van Laanen, C. Wittens, H.J. Houman

*Corresponding author for this work

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Objective: Surgical desobliteration or endophlebectomy of the common femoral vein during deep venous recanalization with complementary polytetrafluoroethylene (PTFE) arteriovenous fistula (AVF), may lead to higher rates of surgical site infection (SSI). It has been reported that closed incisional negative pressure wound therapy (cINPT) may decrease SSI rates after different surgical procedures. The aim of this study was to determine the potential effect of cINPT on the SSI rate of femoral endophlebectomy with a complimentary PTFE AVF.Methods: Patients with recanalization of the femoral-iliac veins and femoral endophlebectomy with a complementary PTFE AVF and postoperative cINPT were identified. SSI, patency, and complication rates were analyzed.Results: This study included 65 patients with a mean age of 41 +/- 14 years. The mean procedure time was 240 +/- 11.9 minutes. Primary patency rate was 69.2% and secondary patency rate was 78.4%. SSI classified as Szilagyi I, II, and III occurred in 7.6% (n = 5), 3% (n = 2), and 7.6% (n = 5), respectively, with an overall SSI rate of 18.2%. Surgical wound revision with the application of a vacuum pump was required in 10.7% (n = 7). A multivariate analysis showed that the duration of the surgical procedure (P =.003) as well as lymphatic fistulas (P =.044) to have a significant impact on the SSI rate.Conclusions: Endophlebectomy with complementary PTFE AVF of the femoral vein is related to an increased rate of lymphatic leakage and SSI. Lymphatic fistula and the duration of surgery could be assessed as relevant influencing factors of SSI. Application of cINPT in this surgical setting may reduce the SSI rate. Despite this potential improvement, SSI rates still limit the clinical success of a deep venous recanalization.
Original languageEnglish
Pages (from-to)89-94
Number of pages6
JournalJournal of Vascular Surgery: Venous and Lymphatic Disorders
Issue number1
Publication statusPublished - 1 Jan 2020


  • arteriovenous fistula
  • cinpt
  • deep venous recanalization
  • disease
  • editors choice
  • endophlebectomy
  • endovenectomy
  • management
  • polytetrafluoroethylene
  • prevena
  • prevention
  • recanalization
  • surgical site infections
  • wound complications
  • Polytetrafluoroethylene
  • Arteriovenous fistula
  • Deep venous recanalization
  • cINPT
  • Prevena
  • Endophlebectomy
  • Surgical site infections

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