Clofazimine Exposure In Vitro Selects Efflux Pump Mutants and Bedaquiline Resistance

Nabila Ismail*, Remco P. H. Peters, Nazir A. Ismail, Shaheed V. Omar

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Article numberARTN e02141-18
Number of pages4
JournalAntimicrobial Agents and Chemotherapy
Volume63
Issue number3
DOIs
Publication statusPublished - Mar 2019

Keywords

  • bedaquiline
  • clofazimine
  • cross-resistance
  • efflux pump mutants
  • MYCOBACTERIUM-TUBERCULOSIS
  • ATP SYNTHASE

Cite this

@article{17cf036159da49a3ad94c803629842ac,
title = "Clofazimine Exposure In Vitro Selects Efflux Pump Mutants and Bedaquiline Resistance",
keywords = "bedaquiline, clofazimine, cross-resistance, efflux pump mutants, MYCOBACTERIUM-TUBERCULOSIS, ATP SYNTHASE",
author = "Nabila Ismail and Peters, {Remco P. H.} and Ismail, {Nazir A.} and Omar, {Shaheed V.}",
year = "2019",
month = "3",
doi = "10.1128/AAC.02141-18",
language = "English",
volume = "63",
journal = "Antimicrobial Agents and Chemotherapy",
issn = "0066-4804",
publisher = "American Society for Microbiology",
number = "3",

}

Clofazimine Exposure In Vitro Selects Efflux Pump Mutants and Bedaquiline Resistance. / Ismail, Nabila; Peters, Remco P. H.; Ismail, Nazir A.; Omar, Shaheed V.

In: Antimicrobial Agents and Chemotherapy, Vol. 63, No. 3, ARTN e02141-18, 03.2019.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Clofazimine Exposure In Vitro Selects Efflux Pump Mutants and Bedaquiline Resistance

AU - Ismail, Nabila

AU - Peters, Remco P. H.

AU - Ismail, Nazir A.

AU - Omar, Shaheed V.

PY - 2019/3

Y1 - 2019/3

KW - bedaquiline

KW - clofazimine

KW - cross-resistance

KW - efflux pump mutants

KW - MYCOBACTERIUM-TUBERCULOSIS

KW - ATP SYNTHASE

U2 - 10.1128/AAC.02141-18

DO - 10.1128/AAC.02141-18

M3 - Article

VL - 63

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

SN - 0066-4804

IS - 3

M1 - ARTN e02141-18

ER -