Clinical pathophysiology of hibernating myocardium.

G.D. Dispersyn, F.C.S. Ramaekers, M. Borgers*

*Corresponding author for this work

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Our current knowledge of the pathophysiology of chronic hibernating myocardium is mainly based on results from clinical studies, because of the absence of appropriate and validated animal models. These clinical observations have given rise to two major controversies: the role of reduced blood flow and that of histological changes in the hibernating segments. In this review, these two subjects will be briefly discussed, and put into the perspective of findings emerging from recently developed animal models. Coron Artery Dis 12:381-385
Original languageEnglish
Pages (from-to)381-385
JournalCoronary Artery Disease
Publication statusPublished - 1 Jan 2001

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