Clinical fractures cluster in time after initial fracture

Tineke A. C. M. Laurs-van Geel*, Jacqueline R. Center, Piet P. Geusens, Geert-Jan Dinant, John A. Eisman

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review


A history of fractures is a well recognised risk factor for a new clinical fracture However this subsequent fracture risk is not constant but fluctuates over time with the greatest increase in the years immediately after the initial fracture followed by a gradual waning of risk toward the population risk The clustering of fractures occurred regardless of age gender and initial fracture location It is therefore likely that fracture risk models which take into account this fluctuation of fracture risk over time will be more relevant in predicting an individual s subsequent fracture risk Regardless of the cause of this clustering these studies all strongly support the need for early action after an initial fracture to reduce the preventable risk of subsequent fractures with medical interventions that have been shown to immediately decrease the risk of fractures
Original languageEnglish
Pages (from-to)339-342
Issue number4
Publication statusPublished - Dec 2010


  • Vertebral fracture
  • Hip fracture
  • Any fracture
  • Subsequent fracture risk
  • Elderly men and women

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