Clinical experiences with peritoneal carcinomatosis treatment using cytoreductive surgery and hyperthermic intraperitoneal chemotherapy

Peritonitis carcinomatosa (PC) is a metastatic disease pattern associated with various types of primary tumours and very low survival rates. Since the combination of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy (CRS + HIPEC) was introduced in the previous century, patients have been offered a chance of prolonged survival and sometimes recovery, despite the fact that most of them are not eligible for this type of treatment. This dissertation tries to explain the selection of patients with peritoneal cancer of colorectal origin who are eligible for this type of treatment and who are not, thereby showing in which patients this type of treatment is effective and in which patients it is not.