Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants

Birke J. Benedikter, Charlotte Volgers, Pascalle H. van Eijck, Emiel F. M. Wouters, Paul H. M. Savelkoul, Niki L. Reynaert, Guido R. M. M. Haenen, Gernot G. U. Rohde, Antje R. Weseler, Frank R. M. Stassen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)334-344
Number of pages11
JournalFree Radical Biology and Medicine
Volume108
DOIs
Publication statusPublished - Jul 2017

Keywords

  • Extracellular vesicles
  • EV
  • COPD
  • Lung
  • Chronic inflammation
  • Oxidative stress
  • Acrolein
  • DTNB
  • Airway epithelial cells
  • PROTEIN-DISULFIDE-ISOMERASE
  • CIRCULATING ENDOTHELIAL MICROPARTICLES
  • OBSTRUCTIVE PULMONARY-DISEASE
  • N-ACETYLCYSTEINE
  • EXTRACELLULAR VESICLES
  • OXIDATIVE STRESS
  • IMMUNE-RESPONSES
  • EPITHELIAL-CELLS
  • PLASMA-MEMBRANE
  • FREE-RADICALS

Cite this

@article{7810d121f33740a4b5ea8cee3158791d,
title = "Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants",
keywords = "Extracellular vesicles, EV, COPD, Lung, Chronic inflammation, Oxidative stress, Acrolein, DTNB, Airway epithelial cells, PROTEIN-DISULFIDE-ISOMERASE, CIRCULATING ENDOTHELIAL MICROPARTICLES, OBSTRUCTIVE PULMONARY-DISEASE, N-ACETYLCYSTEINE, EXTRACELLULAR VESICLES, OXIDATIVE STRESS, IMMUNE-RESPONSES, EPITHELIAL-CELLS, PLASMA-MEMBRANE, FREE-RADICALS",
author = "Benedikter, {Birke J.} and Charlotte Volgers and {van Eijck}, {Pascalle H.} and Wouters, {Emiel F. M.} and Savelkoul, {Paul H. M.} and Reynaert, {Niki L.} and Haenen, {Guido R. M. M.} and Rohde, {Gernot G. U.} and Weseler, {Antje R.} and Stassen, {Frank R. M.}",
year = "2017",
month = "7",
doi = "10.1016/j.freeradbiomed.2017.03.026",
language = "English",
volume = "108",
pages = "334--344",
journal = "Free Radical Biology and Medicine",
issn = "0891-5849",
publisher = "Elsevier Science",

}

TY - JOUR

T1 - Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants

AU - Benedikter, Birke J.

AU - Volgers, Charlotte

AU - van Eijck, Pascalle H.

AU - Wouters, Emiel F. M.

AU - Savelkoul, Paul H. M.

AU - Reynaert, Niki L.

AU - Haenen, Guido R. M. M.

AU - Rohde, Gernot G. U.

AU - Weseler, Antje R.

AU - Stassen, Frank R. M.

PY - 2017/7

Y1 - 2017/7

KW - Extracellular vesicles

KW - EV

KW - COPD

KW - Lung

KW - Chronic inflammation

KW - Oxidative stress

KW - Acrolein

KW - DTNB

KW - Airway epithelial cells

KW - PROTEIN-DISULFIDE-ISOMERASE

KW - CIRCULATING ENDOTHELIAL MICROPARTICLES

KW - OBSTRUCTIVE PULMONARY-DISEASE

KW - N-ACETYLCYSTEINE

KW - EXTRACELLULAR VESICLES

KW - OXIDATIVE STRESS

KW - IMMUNE-RESPONSES

KW - EPITHELIAL-CELLS

KW - PLASMA-MEMBRANE

KW - FREE-RADICALS

U2 - 10.1016/j.freeradbiomed.2017.03.026

DO - 10.1016/j.freeradbiomed.2017.03.026

M3 - Article

VL - 108

SP - 334

EP - 344

JO - Free Radical Biology and Medicine

JF - Free Radical Biology and Medicine

SN - 0891-5849

ER -