Cigarette smoke extract induced exosome release is mediated by depletion of exofacial thiols and can be inhibited by thiol-antioxidants

Birke J. Benedikter, Charlotte Volgers, Pascalle H. van Eijck, Emiel F. M. Wouters, Paul H. M. Savelkoul, Niki L. Reynaert, Guido R. M. M. Haenen, Gernot G. U. Rohde, Antje R. Weseler, Frank R. M. Stassen*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

Original languageEnglish
Pages (from-to)334-344
Number of pages11
JournalFree Radical Biology and Medicine
Volume108
DOIs
Publication statusPublished - Jul 2017

Keywords

  • Extracellular vesicles
  • EV
  • COPD
  • Lung
  • Chronic inflammation
  • Oxidative stress
  • Acrolein
  • DTNB
  • Airway epithelial cells
  • PROTEIN-DISULFIDE-ISOMERASE
  • CIRCULATING ENDOTHELIAL MICROPARTICLES
  • OBSTRUCTIVE PULMONARY-DISEASE
  • N-ACETYLCYSTEINE
  • EXTRACELLULAR VESICLES
  • OXIDATIVE STRESS
  • IMMUNE-RESPONSES
  • EPITHELIAL-CELLS
  • PLASMA-MEMBRANE
  • FREE-RADICALS

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