Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

Annerieke S. R. Sierksma; Kris Rutten; Sebastian Sydlik; Somayeh Rostamian; Harry W. M. Steinbusch; Daniel L. A. van den Hove; Jos Prickaerts

doi:10.1016/j.neuropharm.2012.06.048

Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

Annerieke S. R. Sierksma, Kris Rutten, Sebastian Sydlik, Somayeh Rostamian, Harry W. M. Steinbusch, Daniel L. A. van den Hove, Jos Prickaerts^*

^*Corresponding author for this work

MHeNs School for Mental Health and Neuroscience

Research output: Contribution to journal › Article › Academic › peer-review

57 Citations (Web of Science)

Original language	English
Pages (from-to)	124-136
Journal	Neuropharmacology
Volume	64
DOIs	https://doi.org/10.1016/j.neuropharm.2012.06.048
Publication status	Published - Jan 2013

Keywords

Phosphodiesterase inhibitors (PDEIs)
Alzheimer's disease (AD)
Cognition
CREB
BDNF
APPswe/PS1dE9

Access to Document

10.1016/j.neuropharm.2012.06.048

Cite this

@article{b5b4cdb3f50049c48a0ff9e0a6535e3d,

title = "Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease",

keywords = "Phosphodiesterase inhibitors (PDEIs), Alzheimer's disease (AD), Cognition, CREB, BDNF, APPswe/PS1dE9",

author = "Sierksma, {Annerieke S. R.} and Kris Rutten and Sebastian Sydlik and Somayeh Rostamian and Steinbusch, {Harry W. M.} and {van den Hove}, {Daniel L. A.} and Jos Prickaerts",

year = "2013",

month = jan,

doi = "10.1016/j.neuropharm.2012.06.048",

language = "English",

volume = "64",

pages = "124--136",

journal = "Neuropharmacology",

issn = "0028-3908",

publisher = "Elsevier Science",

}

Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease. / Sierksma, Annerieke S. R.; Rutten, Kris; Sydlik, Sebastian; Rostamian, Somayeh; Steinbusch, Harry W. M.; van den Hove, Daniel L. A.; Prickaerts, Jos.

In: Neuropharmacology, Vol. 64, 01.2013, p. 124-136.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

AU - Sierksma, Annerieke S. R.

AU - Rutten, Kris

AU - Sydlik, Sebastian

AU - Rostamian, Somayeh

AU - Steinbusch, Harry W. M.

AU - van den Hove, Daniel L. A.

AU - Prickaerts, Jos

PY - 2013/1

Y1 - 2013/1

KW - Phosphodiesterase inhibitors (PDEIs)

KW - Alzheimer's disease (AD)

KW - Cognition

KW - CREB

KW - BDNF

KW - APPswe/PS1dE9

U2 - 10.1016/j.neuropharm.2012.06.048

DO - 10.1016/j.neuropharm.2012.06.048

M3 - Article

VL - 64

SP - 124

EP - 136

JO - Neuropharmacology

JF - Neuropharmacology

SN - 0028-3908

ER -