Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

Annerieke S. R. Sierksma, Kris Rutten, Sebastian Sydlik, Somayeh Rostamian, Harry W. M. Steinbusch, Daniel L. A. van den Hove, Jos Prickaerts

Research output: Contribution to journalArticleAcademicpeer-review

36 Citations (Scopus)
Original languageEnglish
Pages (from-to)124-136
JournalNeuropharmacology
Volume64
DOIs
Publication statusPublished - Jan 2013

Keywords

  • Phosphodiesterase inhibitors (PDEIs)
  • Alzheimer's disease (AD)
  • Cognition
  • CREB
  • BDNF
  • APPswe/PS1dE9

Cite this

@article{b5b4cdb3f50049c48a0ff9e0a6535e3d,
title = "Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease",
keywords = "Phosphodiesterase inhibitors (PDEIs), Alzheimer's disease (AD), Cognition, CREB, BDNF, APPswe/PS1dE9",
author = "Sierksma, {Annerieke S. R.} and Kris Rutten and Sebastian Sydlik and Somayeh Rostamian and Steinbusch, {Harry W. M.} and {van den Hove}, {Daniel L. A.} and Jos Prickaerts",
year = "2013",
month = "1",
doi = "10.1016/j.neuropharm.2012.06.048",
language = "English",
volume = "64",
pages = "124--136",
journal = "Neuropharmacology",
issn = "0028-3908",
publisher = "Elsevier Science",

}

Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease. / Sierksma, Annerieke S. R.; Rutten, Kris; Sydlik, Sebastian; Rostamian, Somayeh; Steinbusch, Harry W. M.; van den Hove, Daniel L. A.; Prickaerts, Jos.

In: Neuropharmacology, Vol. 64, 01.2013, p. 124-136.

Research output: Contribution to journalArticleAcademicpeer-review

TY - JOUR

T1 - Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

AU - Sierksma, Annerieke S. R.

AU - Rutten, Kris

AU - Sydlik, Sebastian

AU - Rostamian, Somayeh

AU - Steinbusch, Harry W. M.

AU - van den Hove, Daniel L. A.

AU - Prickaerts, Jos

PY - 2013/1

Y1 - 2013/1

KW - Phosphodiesterase inhibitors (PDEIs)

KW - Alzheimer's disease (AD)

KW - Cognition

KW - CREB

KW - BDNF

KW - APPswe/PS1dE9

U2 - 10.1016/j.neuropharm.2012.06.048

DO - 10.1016/j.neuropharm.2012.06.048

M3 - Article

VL - 64

SP - 124

EP - 136

JO - Neuropharmacology

JF - Neuropharmacology

SN - 0028-3908

ER -