Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

Annerieke S. R. Sierksma; Kris Rutten; Sebastian Sydlik; Somayeh Rostamian; Harry W. M. Steinbusch; Daniel L. A. van den Hove; Jos Prickaerts

doi:10.1016/j.neuropharm.2012.06.048

Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

Annerieke S. R. Sierksma, Kris Rutten, Sebastian Sydlik, Somayeh Rostamian, Harry W. M. Steinbusch, Daniel L. A. van den Hove, Jos Prickaerts

MHeNs School for Mental Health and Neuroscience

Research output: Contribution to journal › Article › Academic › peer-review

Original language	English
Pages (from-to)	124-136
Journal	Neuropharmacology
Volume	64
DOIs	https://doi.org/10.1016/j.neuropharm.2012.06.048
Publication status	Published - Jan 2013

Keywords

Phosphodiesterase inhibitors (PDEIs)
Alzheimer's disease (AD)
Cognition
CREB
BDNF
APPswe/PS1dE9

Access to Document

10.1016/j.neuropharm.2012.06.048

Cite this

Sierksma, A. S. R., Rutten, K., Sydlik, S., Rostamian, S., Steinbusch, H. W. M., van den Hove, D. L. A., & Prickaerts, J. (2013). Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease. Neuropharmacology, 64, 124-136. https://doi.org/10.1016/j.neuropharm.2012.06.048

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title = "Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease",

keywords = "Phosphodiesterase inhibitors (PDEIs), Alzheimer's disease (AD), Cognition, CREB, BDNF, APPswe/PS1dE9",

author = "Sierksma, {Annerieke S. R.} and Kris Rutten and Sebastian Sydlik and Somayeh Rostamian and Steinbusch, {Harry W. M.} and {van den Hove}, {Daniel L. A.} and Jos Prickaerts",

year = "2013",

month = jan,

doi = "10.1016/j.neuropharm.2012.06.048",

language = "English",

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pages = "124--136",

journal = "Neuropharmacology",

issn = "0028-3908",

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Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease. / Sierksma, Annerieke S. R.; Rutten, Kris; Sydlik, Sebastian; Rostamian, Somayeh; Steinbusch, Harry W. M.; van den Hove, Daniel L. A.; Prickaerts, Jos.

In: Neuropharmacology, Vol. 64, 01.2013, p. 124-136.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Chronic phosphodiesterase type 2 inhibition improves memory in the APPswe/PS1dE9 mouse model of Alzheimer's disease

AU - Sierksma, Annerieke S. R.

AU - Rutten, Kris

AU - Sydlik, Sebastian

AU - Rostamian, Somayeh

AU - Steinbusch, Harry W. M.

AU - van den Hove, Daniel L. A.

AU - Prickaerts, Jos

PY - 2013/1

Y1 - 2013/1

KW - Phosphodiesterase inhibitors (PDEIs)

KW - Alzheimer's disease (AD)

KW - Cognition

KW - CREB

KW - BDNF

KW - APPswe/PS1dE9

U2 - 10.1016/j.neuropharm.2012.06.048

DO - 10.1016/j.neuropharm.2012.06.048

M3 - Article

VL - 64

SP - 124

EP - 136

JO - Neuropharmacology

JF - Neuropharmacology

SN - 0028-3908

ER -