Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives

T. Strekalova; Y.Z. Liu; D. Kiselev; S. Khairuddin; J.L.Y. Chiu; J. Lam; Y.S. Chan; D. Pavlov; A. Proshin; K.P. Lesch; D.C. Anthony; L.W. Lim

doi:10.1007/s00213-021-05982-w

Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives

T. Strekalova^*, Y.Z. Liu, D. Kiselev, S. Khairuddin, J.L.Y. Chiu, J. Lam^*, Y.S. Chan, D. Pavlov, A. Proshin, K.P. Lesch, D.C. Anthony, L.W. Lim^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › Academic › peer-review

5 Citations (Web of Science)

Original language	English
Pages (from-to)	663-693
Number of pages	31
Journal	Psychopharmacology
Volume	239
Issue number	3
Early online date	24 Jan 2022
DOIs	https://doi.org/10.1007/s00213-021-05982-w
Publication status	Published - Mar 2022

Keywords

Chronic mild stress (CMS)
Depression
Sucrose test
Anhedonia
Forced swimming
Open field
Inter-individual variability
Stress resilience
Rat
ANXIETY-LIKE BEHAVIOR
ANTIDEPRESSANT-LIKE ACTIVITY
MALE WISTAR RATS
FORCED-SWIM TEST
ANIMAL-MODELS
INDUCED ANHEDONIA
UNPREDICTABLE STRESS
SUCROSE CONSUMPTION
HEART-RATE
PREFRONTAL CORTEX

Access to Document

10.1007/s00213-021-05982-wLicence: CC BY

Cite this

@article{c2865b26f62d4ed0abe9e753c7740fe0,

title = "Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives",

keywords = "Chronic mild stress (CMS), Depression, Sucrose test, Anhedonia, Forced swimming, Open field, Inter-individual variability, Stress resilience, Rat, ANXIETY-LIKE BEHAVIOR, ANTIDEPRESSANT-LIKE ACTIVITY, MALE WISTAR RATS, FORCED-SWIM TEST, ANIMAL-MODELS, INDUCED ANHEDONIA, UNPREDICTABLE STRESS, SUCROSE CONSUMPTION, HEART-RATE, PREFRONTAL CORTEX",

author = "T. Strekalova and Y.Z. Liu and D. Kiselev and S. Khairuddin and J.L.Y. Chiu and J. Lam and Y.S. Chan and D. Pavlov and A. Proshin and K.P. Lesch and D.C. Anthony and L.W. Lim",

year = "2022",

month = mar,

doi = "10.1007/s00213-021-05982-w",

language = "English",

volume = "239",

pages = "663--693",

journal = "Psychopharmacology",

issn = "0033-3158",

publisher = "Springer",

number = "3",

}

Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives. / Strekalova, T.; Liu, Y.Z.; Kiselev, D.; Khairuddin, S.; Chiu, J.L.Y.; Lam, J.; Chan, Y.S.; Pavlov, D.; Proshin, A.; Lesch, K.P.; Anthony, D.C.; Lim, L.W.

In: Psychopharmacology, Vol. 239, No. 3, 03.2022, p. 663-693.

Research output: Contribution to journal › Review article › Academic › peer-review

TY - JOUR

T1 - Chronic mild stress paradigm as a rat model of depression: facts, artifacts, and future perspectives

AU - Strekalova, T.

AU - Liu, Y.Z.

AU - Kiselev, D.

AU - Khairuddin, S.

AU - Chiu, J.L.Y.

AU - Lam, J.

AU - Chan, Y.S.

AU - Pavlov, D.

AU - Proshin, A.

AU - Lesch, K.P.

AU - Anthony, D.C.

AU - Lim, L.W.

PY - 2022/3

Y1 - 2022/3

KW - Chronic mild stress (CMS)

KW - Depression

KW - Sucrose test

KW - Anhedonia

KW - Forced swimming

KW - Open field

KW - Inter-individual variability

KW - Stress resilience

KW - Rat

KW - ANXIETY-LIKE BEHAVIOR

KW - ANTIDEPRESSANT-LIKE ACTIVITY

KW - MALE WISTAR RATS

KW - FORCED-SWIM TEST

KW - ANIMAL-MODELS

KW - INDUCED ANHEDONIA

KW - UNPREDICTABLE STRESS

KW - SUCROSE CONSUMPTION

KW - HEART-RATE

KW - PREFRONTAL CORTEX

U2 - 10.1007/s00213-021-05982-w

DO - 10.1007/s00213-021-05982-w

M3 - Review article

C2 - 35072761

VL - 239

SP - 663

EP - 693

JO - Psychopharmacology

JF - Psychopharmacology

SN - 0033-3158

IS - 3

ER -